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Caveolin-1 induces lamellipodia formation via an Akt-dependent pathway
BACKGROUND: The enhancement of migration is critical for facilitating cancer cell metastasis. METHOD: Lung cancer H23 cells were transfected with either a caveolin-1 (Cav-1) overexpression or shCav-1 plasmid and further subjected to cell migration assays and lamellipodia characterization. The regula...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064105/ https://www.ncbi.nlm.nih.gov/pubmed/24955034 http://dx.doi.org/10.1186/1475-2867-14-52 |