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Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb

In mammals, an array of MEF2C proteins is generated by alternative splicing (AS), yet specific functions have not been ascribed to each isoform. Teleost fish possess two MEF2C paralogues, mef2ca and mef2cb. In zebrafish, the Mef2cs function to promote cardiomyogenic differentiation and myofibrilloge...

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Detalles Bibliográficos
Autores principales: Ganassi, M., Badodi, S., Polacchini, A., Baruffaldi, F., Battini, R., Hughes, S.M., Hinits, Y., Molinari, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064114/
https://www.ncbi.nlm.nih.gov/pubmed/24844180
http://dx.doi.org/10.1016/j.bbagrm.2014.05.003