Cargando…
The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity
The primary cilium is an organelle acting as a master regulator of cellular signalling. We have previously shown that disruption of primary cilia assembly, through targeting intraflagellar transport, is associated with muted nitric oxide and prostaglandin responses to the inflammatory cytokine inter...
Autores principales: | Wann, A.K.T., Chapple, J.P., Knight, M.M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064300/ https://www.ncbi.nlm.nih.gov/pubmed/24726893 http://dx.doi.org/10.1016/j.cellsig.2014.04.004 |
Ejemplares similares
-
A role for IFT88/the primary cilium in the inflammatory response to interleukin-1
por: Wann, AKT, et al.
Publicado: (2012) -
The primary cilium conducts chondrocyte mechanotransduction
por: Wann, AKT, et al.
Publicado: (2012) -
Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium
por: Wann, Angus KT, et al.
Publicado: (2013) -
Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation
por: Fu, S., et al.
Publicado: (2019) -
IKKβ/NF-κB and the miscreant macrophage
por: Timmer, Anjuli M., et al.
Publicado: (2008)