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The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity

The primary cilium is an organelle acting as a master regulator of cellular signalling. We have previously shown that disruption of primary cilia assembly, through targeting intraflagellar transport, is associated with muted nitric oxide and prostaglandin responses to the inflammatory cytokine inter...

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Detalles Bibliográficos
Autores principales: Wann, A.K.T., Chapple, J.P., Knight, M.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064300/
https://www.ncbi.nlm.nih.gov/pubmed/24726893
http://dx.doi.org/10.1016/j.cellsig.2014.04.004

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