Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

BACKGROUND: Human papillomavirus positive (HPV+) head and neck squamous cell carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and epidemiological entity. Understanding the genetic basis of this specific subtype of cancer could allow therapeutic targeting of affected pathway...

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Detalles Bibliográficos
Autores principales: Lechner, Matthias, Frampton, Garrett M, Fenton, Tim, Feber, Andrew, Palmer, Gary, Jay, Amrita, Pillay, Nischalan, Forster, Martin, Cronin, Maureen T, Lipson, Doron, Miller, Vincent A, Brennan, Timothy A, Henderson, Stephen, Vaz, Francis, O'Flynn, Paul, Kalavrezos, Nicholas, Yelensky, Roman, Beck, Stephan, Stephens, Philip J, Boshoff, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064312/
https://www.ncbi.nlm.nih.gov/pubmed/23718828
http://dx.doi.org/10.1186/gm453

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