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Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling
BACKGROUND: Glucocorticoids, such as prednisolone, are widely used anti-inflammatory drugs, but therapy is hampered by a broad range of metabolic side effects including skeletal muscle wasting and insulin resistance. Therefore, development of improved synthetic glucocorticoids that display similar e...
Autores principales: | Ellero-Simatos, Sandrine, Szymańska, Ewa, Rullmann, Ton, Dokter, Wim HA, Ramaker, Raymond, Berger, Ruud, van Iersel, Thijs MP, Smilde, Age K, Hankemeier, Thomas, Alkema, Wynand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064315/ https://www.ncbi.nlm.nih.gov/pubmed/23199229 http://dx.doi.org/10.1186/gm395 |
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