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MRI-based measurements of aerosol deposition in the lung of healthy and elastase-treated rats

Aerosolized drugs are increasingly being used to treat chronic lung diseases or to deliver therapeutics systemically through the lung. The influence of disease, such as emphysema, on particle deposition is not fully understood. With the use of magnetic resonance imaging (MRI), the deposition pattern...

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Detalles Bibliográficos
Autores principales: Oakes, Jessica M., Breen, Ellen C., Scadeng, Miriam, Tchantchou, Ghislain S., Darquenne, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064380/
https://www.ncbi.nlm.nih.gov/pubmed/24790020
http://dx.doi.org/10.1152/japplphysiol.01165.2013