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Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct

INTRODUCTION: Even now, cystic duct cancer (CDC) as defined by Farrar is rare and has a better prognosis than gallbladder cancer, although CDC as defined by Ozden et al., the definition of which could apply to early and advanced cases of CDC, is not rare and has a poorer prognosis than the CDC defin...

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Autores principales: Komori, Shuji, Tsuchiya, Juji, Kumazawa, Iwao, Kawagoe, Hajime, Nishio, Kimitoshi, Misao, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064396/
https://www.ncbi.nlm.nih.gov/pubmed/24858978
http://dx.doi.org/10.1016/j.ijscr.2014.04.022
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author Komori, Shuji
Tsuchiya, Juji
Kumazawa, Iwao
Kawagoe, Hajime
Nishio, Kimitoshi
Misao, Yuki
author_facet Komori, Shuji
Tsuchiya, Juji
Kumazawa, Iwao
Kawagoe, Hajime
Nishio, Kimitoshi
Misao, Yuki
author_sort Komori, Shuji
collection PubMed
description INTRODUCTION: Even now, cystic duct cancer (CDC) as defined by Farrar is rare and has a better prognosis than gallbladder cancer, although CDC as defined by Ozden et al., the definition of which could apply to early and advanced cases of CDC, is not rare and has a poorer prognosis than the CDC defined by Farrar. PRESENTATION OF CASE: A 78-year-old woman with no complaints was found to have a tumor restricted to the cystic duct. Three cytology examinations of the patient's bile could not establish that the tumor was an adenocarcinoma. However, adenocarcinoma was suspected due to the hypervascularity shown on contrast-enhanced computed tomography. Cholecystectomy and extrahepatic bile duct resection with D2 lymph node dissection was performed. The pathological study revealed it to be CDC. Her postoperative course has been uneventful and without recurrence for 21 months. DISCUSSION: At their first medical examination, many CDC patients are found to have such advanced spread of the cancer to adjacent organs that an extended operation might be necessary. As in our case, better patient outcome results when no lymph node or remote metastasis is present. CONCLUSION: Diagnosing CDC as early as possible contributes to curative resections and favorable patient outcomes and also allows surgeons to recommend a mini-invasive procedure to their patients rather than extended resection including that of adjacent organs.
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spelling pubmed-40643962014-06-23 Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct Komori, Shuji Tsuchiya, Juji Kumazawa, Iwao Kawagoe, Hajime Nishio, Kimitoshi Misao, Yuki Int J Surg Case Rep Article INTRODUCTION: Even now, cystic duct cancer (CDC) as defined by Farrar is rare and has a better prognosis than gallbladder cancer, although CDC as defined by Ozden et al., the definition of which could apply to early and advanced cases of CDC, is not rare and has a poorer prognosis than the CDC defined by Farrar. PRESENTATION OF CASE: A 78-year-old woman with no complaints was found to have a tumor restricted to the cystic duct. Three cytology examinations of the patient's bile could not establish that the tumor was an adenocarcinoma. However, adenocarcinoma was suspected due to the hypervascularity shown on contrast-enhanced computed tomography. Cholecystectomy and extrahepatic bile duct resection with D2 lymph node dissection was performed. The pathological study revealed it to be CDC. Her postoperative course has been uneventful and without recurrence for 21 months. DISCUSSION: At their first medical examination, many CDC patients are found to have such advanced spread of the cancer to adjacent organs that an extended operation might be necessary. As in our case, better patient outcome results when no lymph node or remote metastasis is present. CONCLUSION: Diagnosing CDC as early as possible contributes to curative resections and favorable patient outcomes and also allows surgeons to recommend a mini-invasive procedure to their patients rather than extended resection including that of adjacent organs. Elsevier 2014-04-30 /pmc/articles/PMC4064396/ /pubmed/24858978 http://dx.doi.org/10.1016/j.ijscr.2014.04.022 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Komori, Shuji
Tsuchiya, Juji
Kumazawa, Iwao
Kawagoe, Hajime
Nishio, Kimitoshi
Misao, Yuki
Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct
title Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct
title_full Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct
title_fullStr Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct
title_full_unstemmed Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct
title_short Preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct
title_sort preoperative diagnosis of an asymptomatic cancer restricted to the cystic duct
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064396/
https://www.ncbi.nlm.nih.gov/pubmed/24858978
http://dx.doi.org/10.1016/j.ijscr.2014.04.022
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