Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy

Spinal and bulbar muscular atrophy is an X-linked degenerative motor neuron disease caused by an abnormal expansion in the polyglutamine encoding CAG repeat of the androgen receptor gene. There is evidence implicating endoplasmic reticulum stress in the development and progression of neurodegenerati...

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Detalles Bibliográficos
Autores principales: Montague, Karli, Malik, Bilal, Gray, Anna L., La Spada, Albert R., Hanna, Michael G., Szabadkai, Gyorgy, Greensmith, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065020/
https://www.ncbi.nlm.nih.gov/pubmed/24898351
http://dx.doi.org/10.1093/brain/awu114

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