Hearts from Mice Fed a Non-Obesogenic High-Fat Diet Exhibit Changes in Their Oxidative State, Calcium and Mitochondria in Parallel with Increased Susceptibility to Reperfusion Injury

RATIONALE: High-fat diet with obesity-associated co-morbidities triggers cardiac remodeling and renders the heart more vulnerable to ischemia/reperfusion injury. However, the effect of high-fat diet without obesity and associated co-morbidities is presently unknown. OBJECTIVES: To characterize a non...

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Detalles Bibliográficos
Autores principales: Littlejohns, Ben, Pasdois, Philippe, Duggan, Simon, Bond, Andrew R., Heesom, Kate, Jackson, Christopher L., Angelini, Gianni D., Halestrap, Andrew P., Suleiman, M.-Saadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065057/
https://www.ncbi.nlm.nih.gov/pubmed/24950187
http://dx.doi.org/10.1371/journal.pone.0100579

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