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microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer
BACKGROUND: miR-139-5p was identified to be significantly down-regulated in colon tumor tissues by miRNA array. We aimed to clarify its biological function, molecular mechanisms and direct target gene in colorectal cancer (CRC). METHODS: The biological function of miR-139-5p was examined by cell gro...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065091/ https://www.ncbi.nlm.nih.gov/pubmed/24885920 http://dx.doi.org/10.1186/1476-4598-13-124 |