Cargando…

microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer

BACKGROUND: miR-139-5p was identified to be significantly down-regulated in colon tumor tissues by miRNA array. We aimed to clarify its biological function, molecular mechanisms and direct target gene in colorectal cancer (CRC). METHODS: The biological function of miR-139-5p was examined by cell gro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lijing, Dong, Yujuan, Zhu, Nana, Tsoi, Ho, Zhao, Zengren, Wu, Chung Wah, Wang, Kunning, Zheng, Shu, Ng, Simon SM, Chan, Francis KL, Sung, Joseph JY, Yu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065091/ https://www.ncbi.nlm.nih.gov/pubmed/24885920 http://dx.doi.org/10.1186/1476-4598-13-124

Ejemplares similares

MicroRNA dysregulation as a prognostic biomarker in colorectal cancer
por: Dong, Yujuan, et al.
Publicado: (2014)

Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma
por: Kang, Wei, et al.
Publicado: (2015)

MicroRNA-139-5P inhibits human prostate cancer cell proliferation by targeting Notch1
por: Sun, Qian, et al.
Publicado: (2018)

Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP–WT1–TBL1 axis
por: Zhang, Jingwan, et al.
Publicado: (2016)

PM2.5 downregulates MicroRNA-139-5p and induces EMT in Bronchiolar Epithelium Cells by targeting Notch1
por: Wang, Yunxia, et al.
Publicado: (2020)

MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1
por: Song, Mingxu, et al.
Publicado: (2014)

Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer
por: Otani, Koji, et al.
Publicado: (2014)

Correction to: MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1
por: Song, Mingxu, et al.
Publicado: (2021)

microRNA-20a in human faeces as a non-invasive biomarker for colorectal cancer
por: Yau, Tung On, et al.
Publicado: (2015)

MicroRNA-139, an Emerging Gate-Keeper in Various Types of Cancer
por: Stavast, Christiaan J., et al.
Publicado: (2022)

Biological effects and clinical characteristics of microRNA-106a in human colorectal cancer
por: He, Yuzheng, et al.
Publicado: (2017)

Tumor-suppressor microRNA-139-5p restrains bladder cancer cell line ECV-304 properties via targeting Connexin 43
por: Chi, Qiang, et al.
Publicado: (2019)

MicroRNA-139-5p acts as a suppressor gene for depression by targeting nuclear receptor subfamily 3, group C, member 1
por: Su, Bing, et al.
Publicado: (2022)

MicroRNA-506 as a tumor suppressor in anaplastic thyroid carcinoma by regulation of WNT and NOTCH signaling pathways
por: Nasrpour Navaei, Zahra, et al.
Publicado: (2023)

Tumor-suppressor role of miR-139-5p in endometrial cancer
por: Liu, JinHui, et al.
Publicado: (2018)

Differential expression of microRNA-675, microRNA-139-3p and microRNA-335 in benign and malignant adrenocortical tumours
por: Schmitz, K J, et al.
Publicado: (2011)

Cyto-biological effects of microRNA-424-5p on human colorectal cancer cells
por: Yan, Weitao, et al.
Publicado: (2020)

Tumor suppressor microRNA-34a inhibits cell proliferation by targeting Notch1 in renal cell carcinoma
por: ZHANG, CHANGCUN, et al.
Publicado: (2014)

Dual tumor‐suppressors miR‐139‐5p and miR‐139‐3p targeting matrix metalloprotease 11 in bladder cancer
por: Yonemori, Masaya, et al.
Publicado: (2016)

An E3 Ubiquitin Ligase RNF139 Serves as a Tumor-Suppressor in Glioma
por: Chen, Xiaofeng, et al.
Publicado: (2021)

The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis
por: Stavast, Christiaan J., et al.
Publicado: (2021)

MicroRNA-139 targets fibronectin 1 to inhibit papillary thyroid carcinoma progression
por: Ye, Ying, et al.
Publicado: (2017)

MicroRNA-139 targets fibronectin 1 to inhibit papillary thyroid carcinoma progression
por: Ye, Ying, et al.
Publicado: (2022)

MicroRNA-34a suppresses colorectal cancer metastasis by regulating Notch signaling
por: Zhang, Xuemei, et al.
Publicado: (2017)

The Inhibition of MicroRNA-139-5p Promoted Osteoporosis of Bone Marrow-Derived Mesenchymal Stem Cells by Targeting Wnt/Beta- Catenin Signaling Pathway by NOTCH1
por: Feng, Yimiao, et al.
Publicado: (2020)

MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome
por: Wang, Kunning, et al.
Publicado: (2016)

MicroRNA-103 Promotes Colorectal Cancer by Targeting Tumor Suppressor DICER and PTEN
por: Geng, Li, et al.
Publicado: (2014)

MiR-139-5p reverses CD44(+)/CD133(+)-associated multidrug resistance by downregulating NOTCH1 in colorectal carcinoma cells
por: Xu, Ke, et al.
Publicado: (2016)

LATS1 exerts tumor suppressor functions via targeting Gli1 in colorectal cancer
por: Shen, Zhengchao, et al.
Publicado: (2021)

MicroRNA-1231 exerts a tumor suppressor role through regulating the EGFR/PI3K/AKT axis in glioma
por: Zhang, Jiale, et al.
Publicado: (2018)

MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia
por: Krowiorz, K, et al.
Publicado: (2016)

Gut mucosal microbiome across stages of colorectal carcinogenesis
por: Nakatsu, Geicho, et al.
Publicado: (2015)

MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation
por: Papangeli, Irinna, et al.
Publicado: (2016)

MicroRNA-139 Suppresses the Tumorigenicity of Triple Negative Breast Cancer Cells by Targeting SOX8
por: Dong, Liangliang, et al.
Publicado: (2020)

MicroRNA-139-3p Inhibits The Growth And Metastasis Of Ovarian Cancer By Inhibiting ELAVL1
por: Xue, Fang, et al.
Publicado: (2019)

Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think
por: Lobry, Camille, et al.
Publicado: (2011)

MicroRNA-139-5p regulates chronic inflammation by suppressing nuclear factor-κB activity to inhibit cell proliferation and invasion in colorectal cancer
por: Zhu, Mingming, et al.
Publicado: (2019)

The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain
por: Wu, Yen-Chi, et al.
Publicado: (2017)

Detection of miRNA as Non-Invasive Biomarkers of Colorectal Cancer
por: Ren, Albert, et al.
Publicado: (2015)

MicroRNA-155 acts as a tumor suppressor in colorectal cancer by targeting CTHRC1 in vitro
por: Liu, Jingtian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dccof4pnc86d03vgqbdikboo8l