Assessment of PALB2 as a Candidate Melanoma Susceptibility Gene

Partner and localizer of BRCA2 (PALB2) interacts with BRCA2 to enable double strand break repair through homologous recombination. Similar to BRCA2, germline mutations in PALB2 have been shown to predispose to Fanconi anaemia as well as pancreatic and breast cancer. The PALB2/BRCA2 protein interacti...

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Detalles Bibliográficos
Autores principales: Aoude, Lauren G., Xu, Mai, Zhao, Zhen Zhen, Kovacs, Michael, Palmer, Jane M., Johansson, Peter, Symmons, Judith, Trent, Jeffrey M., Martin, Nicholas G., Montgomery, Grant W., Brown, Kevin M., Hayward, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065098/
https://www.ncbi.nlm.nih.gov/pubmed/24949998
http://dx.doi.org/10.1371/journal.pone.0100683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065098/
https://www.ncbi.nlm.nih.gov/pubmed/24949998
http://dx.doi.org/10.1371/journal.pone.0100683

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