Cargando…

PEG–Ursolic Acid Conjugate: Synthesis and In Vitro Release Studies

A highly water-soluble macromolecular compound of ursolic acid with monomethoxypoly(ethylene glycol) (mPEG) was prepared. The physicochemical properties and stabilities under different conditions were investigated. By PEG conjugation, greatly increased water solubility was obtained, and the results...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zacchigna, Marina, Cateni, Francesca, Drioli, Sara, Procida, Giuseppe, Altieri, Tiziano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065131/ https://www.ncbi.nlm.nih.gov/pubmed/24959409 http://dx.doi.org/10.3797/scipharm.1309-17

Ejemplares similares

Synthesis and Cytotoxicity Evaluation of DOTA-Conjugates of Ursolic Acid
por: Kahnt, Michael, et al.
Publicado: (2019)

Synthesis and in vitro Cytotoxicity of Novel Ursolic Acid Derivatives
por: Meng, Yanqiu, et al.
Publicado: (2010)

Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP
por: Gao, Angela X., et al.
Publicado: (2014)

Synthesis and Antiplasmodial Activity of Betulinic Acid and Ursolic Acid Analogues
por: Innocente, Adrine M., et al.
Publicado: (2012)

Synthesis, physicochemical characterization, toxicity and efficacy of a PEG conjugate and a hybrid PEG conjugate nanoparticle formulation of the antibiotic moxifloxacin
por: Tshweu, Lesego L., et al.
Publicado: (2020)

Ursolic acid inhibits epithelial-mesenchymal transition in vitro and in vivo
por: Xu, Chang-Geng, et al.
Publicado: (2019)

Synthesis and study the controlled release of etronidazole from the new PEG/NaY and PEG/MCM-41 nanocomposites
por: Zendehdel, Mojgan, et al.
Publicado: (2014)

Ursolic acid in health and disease
por: Seo, Dae Yun, et al.
Publicado: (2018)

Mitochondria-targeted betulinic and ursolic acid derivatives: synthesis and anticancer activity
por: Nedopekina, Darya A., et al.
Publicado: (2017)

In Vitro, In Silico and In Vivo Studies of Ursolic Acid as an Anti-Filarial Agent
por: Kalani, Komal, et al.
Publicado: (2014)

Synthesis and Evaluation of Novel Triterpene Analogues of Ursolic Acid as Potential Antidiabetic Agent
por: Wu, Panpan, et al.
Publicado: (2015)

Doxorubicin-conjugated PLA-PEG-Folate based polymeric micelle for tumor-targeted delivery: Synthesis and in vitro evaluation
por: Hami, Zahra, et al.
Publicado: (2014)

Ursolic Acid Inhibits Proliferation and Induces Apoptosis of Cancer Cells In Vitro and In Vivo
por: Wang, Xuemei, et al.
Publicado: (2011)

Enhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid
por: Kim, Mikyung, et al.
Publicado: (2014)

Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid
por: Son, Juhyeon, et al.
Publicado: (2020)

Co-delivery of Bmi1 small interfering RNA with ursolic acid by folate receptor-targeted cationic liposomes enhances anti-tumor activity of ursolic acid in vitro and in vivo
por: Li, Weijie, et al.
Publicado: (2019)

Synthesis and biological evaluation of novel ursolic acid analogues as potential α-glucosidase inhibitors
por: Wu, Pan-Pan, et al.
Publicado: (2017)

Synthesis, cytotoxicity and anti-inflammatory activity of rhamnose-containing ursolic and betulinic acid saponins
por: Sylla, Balla, et al.
Publicado: (2019)

Antibacterial and Antioxidant Activities of Ursolic Acid and Derivatives
por: do Nascimento, Patrícia G.G., et al.
Publicado: (2014)

Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update
por: Jesus, Jéssica A., et al.
Publicado: (2015)

Ursolic Acid and Its Derivatives as Bioactive Agents
por: Mlala, Sithenkosi, et al.
Publicado: (2019)

Antagonistic effect of ursolic acid on Staphylococcal biofilms
por: Jyothi, J. Shiva, et al.
Publicado: (2018)

Ursolic Acid Analogs as Potential Therapeutics for Cancer
por: Panda, Siva S., et al.
Publicado: (2022)

Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model
por: Yin, Jianhai, et al.
Publicado: (2018)

In Vitro Cytotoxicity of Oleanolic/Ursolic Acids-Loaded in PLGA Nanoparticles in Different Cell Lines
por: Silva, Amélia M., et al.
Publicado: (2019)

Ursolic Acid against Prostate and Urogenital Cancers: A Review of In Vitro and In Vivo Studies
por: Kornel, Amanda, et al.
Publicado: (2023)

Superior anti-neoplastic activities of triacontanol-PEG conjugate: synthesis, characterization and biological evaluations
por: Zhou, Yimeng, et al.
Publicado: (2018)

Synthesis and Operating Optimization of the PEG Conjugate via CuAAC in scCO(2)
por: López, Sonia, et al.
Publicado: (2021)

Ultrasound-assisted Extraction of Ursolic Acid from the Flowers of Ixora coccinia Linn (Rubiaceae) and Antiproliferative Activity of Ursolic Acid and Synthesized Derivatives
por: Alves Monteath, Silvana Amadeu Ferreira, et al.
Publicado: (2017)

PEG Conjugated Zein Nanoparticles for In Vivo Use
por: van Ballegooie, Courtney, et al.
Publicado: (2022)

Ursolic Acid Hydrazide Based Organometallic Complexes: Synthesis, Characterization, Antibacterial, Antioxidant, and Docking Studies
por: Jabeen, Muafia, et al.
Publicado: (2018)

Prazosin-Conjugated Matrices Based on Biodegradable Polymers and α-Amino Acids—Synthesis, Characterization, and in Vitro Release Study
por: Oledzka, Ewa, et al.
Publicado: (2015)

Ursolic Acid Reduces Mycobacterium tuberculosis-Induced Nitric Oxide Release in Human Alveolar A549 cells
por: Zerin, Tamanna, et al.
Publicado: (2015)

Ursolic Acid Ameliorated Neuronal Damage by Restoring Microglia-Activated MMP/TIMP Imbalance in vitro
por: Qiu, Luying, et al.
Publicado: (2023)

Therapeutic effect of ursolic acid in experimental visceral leishmaniasis
por: Jesus, Jéssica A., et al.
Publicado: (2016)

Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis
por: Jesus, Jéssica Adriana, et al.
Publicado: (2020)

Different Forms of Ursolic Acid and Their Effect on Liver Regeneration
por: Žaloudková, Lenka, et al.
Publicado: (2020)

Ursolic and Oleanolic Acids: Plant Metabolites with Neuroprotective Potential
por: Gudoityte, Evelina, et al.
Publicado: (2021)

Ursolic acid: biological functions and application in animal husbandry
por: Liu, Guanhui, et al.
Publicado: (2023)

In Vitro Sustained Release Study of Gallic Acid Coated with Magnetite-PEG and Magnetite-PVA for Drug Delivery System
por: Dorniani, Dena, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_tjl4vusn01b07c4em7k5vrh10g