Cargando…
Filling Up the Heme Pocket Stabilizes Apomyoglobin and Speeds Up Its Folding
[Image: see text] Wild type apomyoglobin folds in at least two steps: the ABGH core rapidly, followed much later by the heme-binding CDEF core. We hypothesize that the evolved heme-binding function of the CDEF core frustrates its folding: it has a smaller contact order and is no more complex topolog...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065233/ https://www.ncbi.nlm.nih.gov/pubmed/24456280 http://dx.doi.org/10.1021/jp412459z |