A Strategy to Identify Dominant Point Mutant Modifiers of a Quantitative Trait

A central goal in the analysis of complex traits is to identify genes that modify a phenotype. Modifiers of a cancer phenotype may act either intrinsically or extrinsically on the salient cell lineage. Germline point mutagenesis by ethylnitrosourea can provide alleles for a gene of interest that inc...

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Detalles Bibliográficos
Autores principales: Dove, William F., Shedlovsky, Alexandra, Clipson, Linda, Amos-Landgraf, James M., Halberg, Richard B., Krentz, Kathleen J., Boehm, Frederick J., Newton, Michael A., Adams, David J., Keane, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065254/
https://www.ncbi.nlm.nih.gov/pubmed/24747760
http://dx.doi.org/10.1534/g3.114.010595

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