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The U5 snRNA Internal Loop 1 Is a Platform for Brr2, Snu114 and Prp8 Protein Binding During U5 snRNP Assembly

The U5 small nuclear ribonucleoprotein particle (snRNP) forms the heart of the spliceosome which is required for intron removal from pre-mRNA. The proteins Prp8, Snu114 and Brr2 all assemble with the U5 small nuclear RNA (snRNA) to produce the U5 snRNP. Successful assembly of the U5 snRNP, then inco...

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Detalles Bibliográficos
Autores principales:	Nancollis, Verity, Ruckshanthi, Jayalath PD, Frazer, Lily Novak, O'Keefe, Raymond T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065371/ https://www.ncbi.nlm.nih.gov/pubmed/23857713 http://dx.doi.org/10.1002/jcb.24625

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