Plexiform neurofibromatosis involving face and oral cavity

Plexiform neurofibromas (PNFs) are one of the most common and debilitating complications of neurofibromatosis type I (NF-I). They account for substantial morbidity, disfigurement, functional impairment and are life threatening. PNFs can also be subjected to transformation into malignant peripheral n...

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Autores principales: Jayachandran, Dorairaj, Sunantha, Selvaraj, Gopalaiah, Hema, Veeraraghavan, Gajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065427/
https://www.ncbi.nlm.nih.gov/pubmed/24959050
http://dx.doi.org/10.4103/0973-029X.131932
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author Jayachandran, Dorairaj
Sunantha, Selvaraj
Gopalaiah, Hema
Veeraraghavan, Gajendra
author_facet Jayachandran, Dorairaj
Sunantha, Selvaraj
Gopalaiah, Hema
Veeraraghavan, Gajendra
author_sort Jayachandran, Dorairaj
collection PubMed
description Plexiform neurofibromas (PNFs) are one of the most common and debilitating complications of neurofibromatosis type I (NF-I). They account for substantial morbidity, disfigurement, functional impairment and are life threatening. PNFs can also be subjected to transformation into malignant peripheral nerve sheath tumor (MPNST). This complication is refractory to treat due to paucity of effective therapies for malignant soft tissue sarcomas in general and also the delay in diagnosis from a preexisting tumor. We report a case of PNF of face involving oral cavity with literature review.
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spelling pubmed-40654272014-06-23 Plexiform neurofibromatosis involving face and oral cavity Jayachandran, Dorairaj Sunantha, Selvaraj Gopalaiah, Hema Veeraraghavan, Gajendra J Oral Maxillofac Pathol Case Report Plexiform neurofibromas (PNFs) are one of the most common and debilitating complications of neurofibromatosis type I (NF-I). They account for substantial morbidity, disfigurement, functional impairment and are life threatening. PNFs can also be subjected to transformation into malignant peripheral nerve sheath tumor (MPNST). This complication is refractory to treat due to paucity of effective therapies for malignant soft tissue sarcomas in general and also the delay in diagnosis from a preexisting tumor. We report a case of PNF of face involving oral cavity with literature review. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4065427/ /pubmed/24959050 http://dx.doi.org/10.4103/0973-029X.131932 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jayachandran, Dorairaj
Sunantha, Selvaraj
Gopalaiah, Hema
Veeraraghavan, Gajendra
Plexiform neurofibromatosis involving face and oral cavity
title Plexiform neurofibromatosis involving face and oral cavity
title_full Plexiform neurofibromatosis involving face and oral cavity
title_fullStr Plexiform neurofibromatosis involving face and oral cavity
title_full_unstemmed Plexiform neurofibromatosis involving face and oral cavity
title_short Plexiform neurofibromatosis involving face and oral cavity
title_sort plexiform neurofibromatosis involving face and oral cavity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065427/
https://www.ncbi.nlm.nih.gov/pubmed/24959050
http://dx.doi.org/10.4103/0973-029X.131932
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AT veeraraghavangajendra plexiformneurofibromatosisinvolvingfaceandoralcavity

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