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An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion
Epithelialmyoepithelial carcinoma (EMEC) is a rare low-grade malignant salivary gland neoplasm that most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here, we present a case of EMEC in a 60-year-old male patient with a huge swelling in the left parotid gland regi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065428/ https://www.ncbi.nlm.nih.gov/pubmed/24959051 http://dx.doi.org/10.4103/0973-029X.131935 |
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author | Sharma, Shubhra Patankar, Sangeeta |
author_facet | Sharma, Shubhra Patankar, Sangeeta |
author_sort | Sharma, Shubhra |
collection | PubMed |
description | Epithelialmyoepithelial carcinoma (EMEC) is a rare low-grade malignant salivary gland neoplasm that most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here, we present a case of EMEC in a 60-year-old male patient with a huge swelling in the left parotid gland region. Clinically and radiologically, it simulated a benign salivary gland neoplasm. However, fine-needle aspiration cytology and histologic examination revealed atypical myoepithelial cells in solid sheets or nests suggestive of epithelial-myoepithelial carcinoma. Diagnosis was further confirmed by positive immunohistochemical staining with calponin (CALP) and periodic acid-Schiff (PAS) for glycogen. |
format | Online Article Text |
id | pubmed-4065428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-40654282014-06-23 An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion Sharma, Shubhra Patankar, Sangeeta J Oral Maxillofac Pathol Case Report Epithelialmyoepithelial carcinoma (EMEC) is a rare low-grade malignant salivary gland neoplasm that most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here, we present a case of EMEC in a 60-year-old male patient with a huge swelling in the left parotid gland region. Clinically and radiologically, it simulated a benign salivary gland neoplasm. However, fine-needle aspiration cytology and histologic examination revealed atypical myoepithelial cells in solid sheets or nests suggestive of epithelial-myoepithelial carcinoma. Diagnosis was further confirmed by positive immunohistochemical staining with calponin (CALP) and periodic acid-Schiff (PAS) for glycogen. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4065428/ /pubmed/24959051 http://dx.doi.org/10.4103/0973-029X.131935 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Sharma, Shubhra Patankar, Sangeeta An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion |
title | An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion |
title_full | An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion |
title_fullStr | An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion |
title_full_unstemmed | An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion |
title_short | An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion |
title_sort | unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065428/ https://www.ncbi.nlm.nih.gov/pubmed/24959051 http://dx.doi.org/10.4103/0973-029X.131935 |
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