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Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis or pregnancy morbidity. Ocular involvement in APS includes a broad spectrum of manifestations involving anterior and posterior segment or the presence of neuroophthalmologic features. Nonarteritic anterior...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065524/ https://www.ncbi.nlm.nih.gov/pubmed/23571268 http://dx.doi.org/10.4103/0301-4738.109535 |
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author | Tugcu, Betul Acar, Nur Coskun, Cigdem Tanrıverdi Celik, Selda Yigit, Fadime Ulviye |
author_facet | Tugcu, Betul Acar, Nur Coskun, Cigdem Tanrıverdi Celik, Selda Yigit, Fadime Ulviye |
author_sort | Tugcu, Betul |
collection | PubMed |
description | Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis or pregnancy morbidity. Ocular involvement in APS includes a broad spectrum of manifestations involving anterior and posterior segment or the presence of neuroophthalmologic features. Nonarteritic anterior ischemic optic neuropathy (NAION) is a very rare finding, and in this report a case having NAION as the prevailing sign of APS is presented. A middle-aged women who presented with visual disturbances in her left eye (LE) and turned out to have the diagnosis of primary APS with the help of rheumatological investigations is discussed. She was treated with oral steroids for NAION in her LE. With systemic and rheumatological work-up, primary APS was diagnosed, and hydroxychloroquine, coumadin, and aspirin were started, after which she remained stable under control. Due to the important diagnostic and therapeutic implications of APS, it should be considered in the differential diagnosis of NAION, particularly when the etiology is uncertain. |
format | Online Article Text |
id | pubmed-4065524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-40655242014-07-01 Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome Tugcu, Betul Acar, Nur Coskun, Cigdem Tanrıverdi Celik, Selda Yigit, Fadime Ulviye Indian J Ophthalmol Brief Communications Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis or pregnancy morbidity. Ocular involvement in APS includes a broad spectrum of manifestations involving anterior and posterior segment or the presence of neuroophthalmologic features. Nonarteritic anterior ischemic optic neuropathy (NAION) is a very rare finding, and in this report a case having NAION as the prevailing sign of APS is presented. A middle-aged women who presented with visual disturbances in her left eye (LE) and turned out to have the diagnosis of primary APS with the help of rheumatological investigations is discussed. She was treated with oral steroids for NAION in her LE. With systemic and rheumatological work-up, primary APS was diagnosed, and hydroxychloroquine, coumadin, and aspirin were started, after which she remained stable under control. Due to the important diagnostic and therapeutic implications of APS, it should be considered in the differential diagnosis of NAION, particularly when the etiology is uncertain. Medknow Publications & Media Pvt Ltd 2014-05 /pmc/articles/PMC4065524/ /pubmed/23571268 http://dx.doi.org/10.4103/0301-4738.109535 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communications Tugcu, Betul Acar, Nur Coskun, Cigdem Tanrıverdi Celik, Selda Yigit, Fadime Ulviye Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome |
title | Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome |
title_full | Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome |
title_fullStr | Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome |
title_full_unstemmed | Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome |
title_short | Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome |
title_sort | nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome |
topic | Brief Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065524/ https://www.ncbi.nlm.nih.gov/pubmed/23571268 http://dx.doi.org/10.4103/0301-4738.109535 |
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