Cargando…

A recombinant adenovirus-based vector elicits a specific humoral immune response against the V3 loop of HIV-1 gp120 in mice through the “Antigen Capsid-Incorporation” strategy

BACKGROUND: Due to potential advantages, human adenoviral vectors have been evaluated pre-clinically as recombinant vaccine vectors against several cancers and infectious diseases, including human immunodeficiency virus (HIV) infection. The V3 loop of HIV-1 glycoprotein 120 (gp120) contains importan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Linlin, Krendelchtchikova, Valentina, Krendelchtchikov, Alexandre, Oster, Robert A, Fujihashi, Kohtaro, Matthews, Qiana L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065546/ https://www.ncbi.nlm.nih.gov/pubmed/24935650 http://dx.doi.org/10.1186/1743-422X-11-112

Ejemplares similares

Development of an Ad5H3 Chimera Using the “Antigen Capsid-Incorporation” Strategy for an Alternative Vaccination Approach
por: Gu, Linlin, et al.
Publicado: (2016)

Multivalent adenoviral vectors which use an antigen capsid-incorporation strategy for HIV vaccination
por: Gu, L, et al.
Publicado: (2012)

Using Multivalent Adenoviral Vectors for HIV Vaccination
por: Gu, Linlin, et al.
Publicado: (2013)

A Novel Vaccine Approach for Chagas Disease Using Rare Adenovirus Serotype 48 Vectors
por: Farrow, Anitra L., et al.
Publicado: (2016)

Epitope Capsid-Incorporation: A New Effective Approach for Vaccine Development for Chagas Disease
por: Matthews, Qiana L., et al.
Publicado: (2016)

Evaluation of adenovirus capsid labeling versus transgene expression
por: Li, Jing, et al.
Publicado: (2010)

Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach
por: Matthews, Qiana L, et al.
Publicado: (2008)

Immunization with Hexon Modified Adenoviral Vectors Integrated with gp83 Epitope Provides Protection against Trypanosoma cruzi Infection
por: Farrow, Anitra L., et al.
Publicado: (2014)

Eliciting neutralizing antibodies with gp120 outer domain
por: Qin, Y, et al.
Publicado: (2012)

Neural stem cell-derived exosomes mediate viral entry
por: Sims, Brian, et al.
Publicado: (2014)

Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 ± IL-15
por: McKee, Hayley J, et al.
Publicado: (2004)

Differential binding of the HIV-1 envelope to phosphatidylserine receptors
por: Gu, Linlin, et al.
Publicado: (2017)

CryoEM Visualization of an Adenovirus Capsid-Incorporated HIV Antigen
por: Flatt, Justin W., et al.
Publicado: (2012)

Engineered gp120 immunogens that elicit VRC01-like antibodies by vaccination
por: Mata-Fink, J, et al.
Publicado: (2012)

Adenovirus-Based Vectors for the Development of Prophylactic and Therapeutic Vaccines
por: Borovjagin, Anton V., et al.
Publicado: (2014)

Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens
por: Klein, Sarah R., et al.
Publicado: (2016)

Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
por: Rusert, Peter, et al.
Publicado: (2011)

Molecular Recognition of CCR5 by an HIV-1 gp120 V3 Loop
por: Tamamis, Phanourios, et al.
Publicado: (2014)

Identification of peptide epitopes of the gp120 protein of HIV-1 capable of inducing cellular and humoral immunity
por: García-Machorro, Jazmín, et al.
Publicado: (2023)

Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells
por: Sims, Brian, et al.
Publicado: (2017)

HIV-1 envelope trimer elicits higher neutralizing antibody responses than monomeric gp120
por: Kovacs, JM, et al.
Publicado: (2012)

Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
por: Sander, Oliver, et al.
Publicado: (2007)

Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with V3 Loop
por: Yokoyama, Masaru, et al.
Publicado: (2012)

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties
por: López de Victoria, Aliana, et al.
Publicado: (2012)

Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2
por: Dicks, Matthew D.J., et al.
Publicado: (2022)

Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host Interactions
por: Weklak, Denice, et al.
Publicado: (2021)

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site
por: Dai, K, et al.
Publicado: (2012)

The Influence of N-Linked Glycans on the Molecular Dynamics of the HIV-1 gp120 V3 Loop
por: Wood, Natasha T., et al.
Publicado: (2013)

Curcumin improves synaptic plasticity impairment induced by HIV-1gp120 V3 loop
por: Shen, Ling-ling, et al.
Publicado: (2015)

Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses
por: Bowder, Dane, et al.
Publicado: (2018)

Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector
por: Khattar, Sunil K., et al.
Publicado: (2013)

Gp120/CD4 Blocking Antibodies Are Frequently Elicited in ART-Naïve Chronically HIV-1 Infected Individuals
por: Carrillo, Jorge, et al.
Publicado: (2015)

Derivation of a Triple Mosaic Adenovirus for Cancer Gene Therapy
por: Tang, Yizhe, et al.
Publicado: (2009)

Perspective on Adenoviruses: Epidemiology, Pathogenicity, and Gene Therapy
por: Crenshaw, Brennetta J., et al.
Publicado: (2019)

Structure-Based Stabilization of HIV-1 gp120 Enhances Humoral Immune Responses to the Induced Co-Receptor Binding Site
por: Dey, Barna, et al.
Publicado: (2009)

Correction: Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector
por: Khattar, Sunil K., et al.
Publicado: (2014)

Retraction: Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector
Publicado: (2020)

Focusing the immune response on the V3 loop of HIV-1 gp120 induces cross-clade neutralizing
por: Zolla-Pazner, Susan, et al.
Publicado: (2006)

Cryptic Determinant of α4β7 Binding in the V2 Loop of HIV-1 gp120
por: Tassaneetrithep, Boonrat, et al.
Publicado: (2014)

Insights into the Structure, Correlated Motions, and Electrostatic Properties of Two HIV-1 gp120 V3 Loops
por: López de Victoria, Aliana, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6p63karktciftvfc2angpo1s9u