MicroRNAs in Autoimmune Diseases

Autoimmune diseases (ADs) are featured by body's immune responses being directed towards its own specific target organs or multiple organ systems, causing persistent inflammation and consequent tissue damage. miRNAs are small noncoding RNAs in a size of approximately 22 nt that play important r...

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Detalles Bibliográficos
Autores principales: Qu, Zigang, Li, Wenhui, Fu, Baoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065654/
https://www.ncbi.nlm.nih.gov/pubmed/24991561
http://dx.doi.org/10.1155/2014/527895
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author Qu, Zigang
Li, Wenhui
Fu, Baoquan
author_facet Qu, Zigang
Li, Wenhui
Fu, Baoquan
author_sort Qu, Zigang
collection PubMed
description Autoimmune diseases (ADs) are featured by body's immune responses being directed towards its own specific target organs or multiple organ systems, causing persistent inflammation and consequent tissue damage. miRNAs are small noncoding RNAs in a size of approximately 22 nt that play important regulatory roles in many organisms by cleavage or translational inhibition of targeted mRNAs. Many miRNAs are reported to be differentially expressed in ADs and may play a pivotal role in regulating immune responses and autoimmunity. In this review, current research progress in the miRNAs in ADs was elucidated.
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spelling pubmed-40656542014-07-02 MicroRNAs in Autoimmune Diseases Qu, Zigang Li, Wenhui Fu, Baoquan Biomed Res Int Review Article Autoimmune diseases (ADs) are featured by body's immune responses being directed towards its own specific target organs or multiple organ systems, causing persistent inflammation and consequent tissue damage. miRNAs are small noncoding RNAs in a size of approximately 22 nt that play important regulatory roles in many organisms by cleavage or translational inhibition of targeted mRNAs. Many miRNAs are reported to be differentially expressed in ADs and may play a pivotal role in regulating immune responses and autoimmunity. In this review, current research progress in the miRNAs in ADs was elucidated. Hindawi Publishing Corporation 2014 2014-06-04 /pmc/articles/PMC4065654/ /pubmed/24991561 http://dx.doi.org/10.1155/2014/527895 Text en Copyright © 2014 Zigang Qu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Qu, Zigang
Li, Wenhui
Fu, Baoquan
MicroRNAs in Autoimmune Diseases
title MicroRNAs in Autoimmune Diseases
title_full MicroRNAs in Autoimmune Diseases
title_fullStr MicroRNAs in Autoimmune Diseases
title_full_unstemmed MicroRNAs in Autoimmune Diseases
title_short MicroRNAs in Autoimmune Diseases
title_sort micrornas in autoimmune diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065654/
https://www.ncbi.nlm.nih.gov/pubmed/24991561
http://dx.doi.org/10.1155/2014/527895
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AT liwenhui micrornasinautoimmunediseases
AT fubaoquan micrornasinautoimmunediseases

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