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Cartilage Dysfunction in ALS Patients as Side Effect of Motion Loss: 3D Mechano-Electrochemical Computational Model
Amyotrophic lateral sclerosis (ALS) is a debilitating motor neuron disease characterized by progressive weakness, muscle atrophy, and fasciculation. This fact results in a continuous degeneration and dysfunction of articular soft tissues. Specifically, cartilage is an avascular and nonneural connect...
Autores principales: | Manzano, Sara, Gaffney, Eamonn A., Doblaré, Manuel, Hamdy Doweidar, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065674/ https://www.ncbi.nlm.nih.gov/pubmed/24991537 http://dx.doi.org/10.1155/2014/179070 |
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