Cargando…

Peripheral Injection of SB203580 Inhibits the Inflammatory-Dependent Synthesis of Proinflammatory Cytokines in the Hypothalamus

The study was designed to determine the effects of peripheral injection of SB203580 on the synthesis of interleukin- (IL-) 1β, IL-6, and tumor necrosis factor (TNF) α in the hypothalamus of ewes during prolonged inflammation. Inflammation was induced by the administration of lipopolysaccharide (LPS)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Herman, Andrzej P., Krawczyńska, Agata, Bochenek, Joanna, Antushevich, Hanna, Herman, Anna, Tomaszewska-Zaremba, Dorota
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065737/ https://www.ncbi.nlm.nih.gov/pubmed/24995301 http://dx.doi.org/10.1155/2014/475152

Ejemplares similares

Acute Effect of Caffeine on the Synthesis of Pro-Inflammatory Cytokines in the Hypothalamus and Choroid Plexus during Endotoxin-Induced Inflammation in a Female Sheep Model
por: Szczepkowska, Aleksandra, et al.
Publicado: (2021)

The Influence of Photoperiod on the Action of Exogenous Leptin on Gene Expression of Proinflammatory Cytokines and Their Receptors in the Thoracic Perivascular Adipose Tissue (PVAT) in Ewes
por: Krawczyńska, Agata, et al.
Publicado: (2019)

Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation
por: Herman, Andrzej P., et al.
Publicado: (2018)

Effect of Central Injection of Neostigmine on the Bacterial Endotoxin Induced Suppression of GnRH/LH Secretion in Ewes during the Follicular Phase of the Estrous Cycle
por: Herman, Andrzej Przemysław, et al.
Publicado: (2019)

Peripheral Inhibitor of AChE, Neostigmine, Prevents the Inflammatory Dependent Suppression of GnRH/LH Secretion during the Follicular Phase of the Estrous Cycle
por: Herman, Andrzej P., et al.
Publicado: (2017)

Effect of Acute and Prolonged Inflammation on the Gene Expression of Proinflammatory Cytokines and Their Receptors in the Anterior Pituitary Gland of Ewes
por: Wojtulewicz, Karolina, et al.
Publicado: (2020)

Endotoxin-induced inflammation disturbs melatonin secretion in ewe
por: Herman, Andrzej Przemysław, et al.
Publicado: (2017)

LPS-Induced Inflammation Potentiates the IL-1β-Mediated Reduction of LH Secretion from the Anterior Pituitary Explants
por: Herman, Andrzej Przemysław, et al.
Publicado: (2013)

The Effect of Leptin on the Blood Hormonal Profile (Cortisol, Insulin, Thyroid Hormones) of the Ewe in Acute Inflammation in Two Different Photoperiodical Conditions
por: Krawczyńska, Agata, et al.
Publicado: (2022)

Anandamide Influences Interleukin-1β Synthesis and IL-1 System Gene Expressions in the Ovine Hypothalamus during Endo-Toxin-Induced Inflammation
por: Tomczyk, Monika, et al.
Publicado: (2021)

Influence of Leptin on the Secretion of Growth Hormone in Ewes under Different Photoperiodic Conditions
por: Wójcik, Maciej, et al.
Publicado: (2023)

Central Interleukin-1β Suppresses the Nocturnal Secretion of Melatonin
por: Herman, A. P., et al.
Publicado: (2016)

Post-Receptor Inhibitors of the GHR-JAK2-STAT Pathway in the Growth Hormone Signal Transduction
por: Wójcik, Maciej, et al.
Publicado: (2018)

Interleukin-1β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study
por: Herman, A. P., et al.
Publicado: (2015)

A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190
por: Glover, Mark, et al.
Publicado: (2010)

In vitro modeling of COPD inflammation and limitation of p38 inhibitor – SB203580
por: Meng, Aihong, et al.
Publicado: (2016)

Effects of Central Injection of Anti-LPS Antibody and Blockade of TLR4 on GnRH/LH Secretion during Immunological Stress in Anestrous Ewes
por: Haziak, Karolina, et al.
Publicado: (2014)

Effect of CD14/TLR4 antagonist on GnRH/LH secretion in ewe during central inflammation induced by intracerebroventricular administration of LPS
por: Haziak, Karolina, et al.
Publicado: (2018)

The Influence of Anandamide on the Anterior Pituitary Hormone Secretion in Ewes—Ex Vivo Study
por: Tomaszewska-Zaremba, Dorota, et al.
Publicado: (2020)

The p38 MAPK inhibitor SB203580 differentially modulates LPS-induced interleukin 6 expression in macrophages
por: Shi, Qinghai, et al.
Publicado: (2015)

SB203580—A Potent p38 MAPK Inhibitor Reduces the Profibrotic Bronchial Fibroblasts Transition Associated with Asthma
por: Paw, Milena, et al.
Publicado: (2021)

Chronic treatment with TNF-α, alone and in combination with Takinib, SB203580 and metformin induce cell death in breast cancer
por: Abdolvand, Maryam, et al.
Publicado: (2023)

Endotoxin-Induced Inflammation Suppresses the Effect of Melatonin on the Release of LH from the Ovine Pars Tuberalis Explants—Ex Vivo Study
por: Wojtulewicz, Karolina, et al.
Publicado: (2017)

The Impact of Photoperiod on the Leptin Sensitivity and Course of Inflammation in the Anterior Pituitary
por: Wójcik, Maciej, et al.
Publicado: (2020)

Inflammation and LPS-Binding Protein Enable the Stimulatory Effect of Endotoxin on Prolactin Secretion in the Ovine Anterior Pituitary: Ex Vivo Study
por: Tomaszewska-Zaremba, Dorota, et al.
Publicado: (2018)

The Effect of Photoperiodic Conditions on GnRH/LH Secretion in Ewes
por: Kopycińska, Kamila, et al.
Publicado: (2022)

SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation
por: Sreekanth, Gopinathan Pillai, et al.
Publicado: (2016)

The p38 MAPK Inhibitor SB203580 Abrogates Tumor Necrosis Factor-Induced Proliferative Expansion of Mouse CD4(+)Foxp3(+) Regulatory T Cells
por: He, Tianzhen, et al.
Publicado: (2018)

Pharmacological Inhibition of p38 MAPK by SB203580 Increases Resistance to Carboplatin in A2780cp Cells and Promotes Growth in Primary Ovarian Cancer Cells
por: Han, Xiaolu, et al.
Publicado: (2018)

Screening of differentially expressed protein kinases in bone marrow endothelial cells and the protective effects of the p38a inhibitor SB203580 on bone marrow in liver fibrosis
por: Gao, Bo, et al.
Publicado: (2016)

Combination of metformin and p38 MAPK inhibitor, SB203580, reduced myocardial ischemia/reperfusion injury in non-obese type 2 diabetic Goto-Kakizaki rats
por: Sanit, Jantira, et al.
Publicado: (2019)

SB203580 increases G-CSF production via a stem-loop destabilizing element in the 3’ untranslated region in macrophages independently of its effect on p38 MAPK activity
por: Chang, Shwu-Fen, et al.
Publicado: (2016)

Photoperiod Affects Leptin Action on the Choroid Plexus in Ewes Challenged with Lipopolysaccharide—Study on the mRNA Level
por: Szczepkowska, Aleksandra, et al.
Publicado: (2020)

Household fear of deportation in relation to chronic stressors and salivary proinflammatory cytokines in Mexican-origin families post-SB 1070
por: Martínez, Airín D., et al.
Publicado: (2018)

Proinflammatory Cytokines in Peritonitis
por: Badiu, DC, et al.
Publicado: (2011)

The Associations between Infertility and Antioxidants, Proinflammatory Cytokines, and Chemokines
por: Chyra-Jach, Dorota, et al.
Publicado: (2018)

Serum concentrations of selected proinflammatory cytokines in children with alopecia areata
por: Tabara, Katarzyna, et al.
Publicado: (2019)

Proinflammatory Cytokines and Potassium Channels in the Kidney
por: Nakamura, Kazuyoshi, et al.
Publicado: (2015)

SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen‐activated protein kinase in olfactory sensory neuronal apoptosis of OVA‐induced allergic rhinitis)
por: Gao, Xian, et al.
Publicado: (2019)

Kinetics of proinflammatory cytokines after intraperitoneal injection of tribromoethanol and a tribromoethanol/xylazine combination in ICR mice
por: Cho, Yoon Ju, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_gen0nlkc9ghet2sfkibhieqb6g