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Prevention and Reversal of Diabetes by All-Trans Retinoid Acid and Exendin-4 in NOD Mice

It has been shown that all-trans retinoid acid (ATRA) hinders the development of autoimmune diabetes by inducing immune tolerance status. Meanwhile, exendin-4 increases beta-cell function and mass. Thus, we hypothesized that ATRA and exendin-4 combination therapy would prevent and reverse autoimmune...

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Detalles Bibliográficos
Autores principales: Juang, Jyuhn-Huarng, Van, Yang-Hau, Kuo, Chien-Hung, Lin, Mei-Yin, Liu, Ying-Hsiu, Chang, Han-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065745/
https://www.ncbi.nlm.nih.gov/pubmed/24995016
http://dx.doi.org/10.1155/2014/435481