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The EUPHRATES trial (Evaluating the Use of Polymyxin B Hemoperfusion in a Randomized controlled trial of Adults Treated for Endotoxemia and Septic shock): study protocol for a randomized controlled trial

BACKGROUND: Septic shock is common and has unacceptably high morbidity, mortality, and associated cost with numerous failed attempts at developing effective therapies. Endotoxin, one of the most potent mediators of sepsis, is found in high levels in approximately 50% of patients with septic shock. P...

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Detalles Bibliográficos
Autores principales: Klein, David J, Foster, Debra, Schorr, Christa A, Kazempour, Kazem, Walker, Paul M, Dellinger, R Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066268/
https://www.ncbi.nlm.nih.gov/pubmed/24916483
http://dx.doi.org/10.1186/1745-6215-15-218