Cargando…
Sitagliptin, a DPP-4 Inhibitor, Acutely Inhibits Intestinal Lipoprotein Particle Secretion in Healthy Humans
The dipeptidyl peptidase-4 inhibitor sitagliptin, an antidiabetic agent, which lowers blood glucose levels, also reduces postprandial lipid excursion after a mixed meal. The underlying mechanism of this effect, however, is not clear. This study examined the production and clearance of triglyceride-r...
Autores principales: | Xiao, Changting, Dash, Satya, Morgantini, Cecilia, Patterson, Bruce W., Lewis, Gary F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066342/ https://www.ncbi.nlm.nih.gov/pubmed/24584549 http://dx.doi.org/10.2337/db13-1654 |
Ejemplares similares
-
Sodium Phenylbutyrate, a Drug With Known Capacity to Reduce Endoplasmic Reticulum Stress, Partially Alleviates Lipid-Induced Insulin Resistance and β-Cell Dysfunction in Humans
por: Xiao, Changting, et al.
Publicado: (2011) -
Effects of Acute Hyperglucagonemia on Hepatic and Intestinal Lipoprotein Production and Clearance in Healthy Humans
por: Xiao, Changting, et al.
Publicado: (2011) -
Diet-Induced Adipose Tissue Inflammation and Liver Steatosis Are Prevented by DPP-4 Inhibition in Diabetic Mice
por: Shirakawa, Jun, et al.
Publicado: (2011) -
The Role of Endogenous Incretin Secretion as Amplifier of Glucose-Stimulated Insulin Secretion in Healthy Subjects and Patients With Type 2 Diabetes
por: Woerle, Hans Juergen, et al.
Publicado: (2012) -
Insulin Acutely Inhibits Intestinal Lipoprotein Secretion in Humans in Part by Suppressing Plasma Free Fatty Acids
por: Pavlic, Mirjana, et al.
Publicado: (2010)