Genetic architecture of retinal and macular degenerative diseases: the promise and challenges of next-generation sequencing

Inherited retinal degenerative diseases (RDDs) display wide variation in their mode of inheritance, underlying genetic defects, age of onset, and phenotypic severity. Molecular mechanisms have not been delineated for many retinal diseases, and treatment options are limited. In most instances, genoty...

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Detalles Bibliográficos
Autores principales: Ratnapriya, Rinki, Swaroop, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066589/
https://www.ncbi.nlm.nih.gov/pubmed/24112618
http://dx.doi.org/10.1186/gm488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066589/
https://www.ncbi.nlm.nih.gov/pubmed/24112618
http://dx.doi.org/10.1186/gm488

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