Translating pharmacogenomics discoveries into the clinic: an implementation framework

The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent st...

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Detalles Bibliográficos
Autores principales: Huang, R Stephanie, Gamazon, Eric R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066637/
https://www.ncbi.nlm.nih.gov/pubmed/24134796
http://dx.doi.org/10.1186/gm497
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author Huang, R Stephanie
Gamazon, Eric R
author_facet Huang, R Stephanie
Gamazon, Eric R
author_sort Huang, R Stephanie
collection PubMed
description The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent study describes a comprehensive system developed by the Coriell Personalized Medicine Collaborative for facilitating the translation of genomic findings into clinical practice, and its application for seven commonly prescribed drugs. See related Research paper, http://genomemedicine.com/content/5/10/93
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spelling pubmed-40666372014-10-18 Translating pharmacogenomics discoveries into the clinic: an implementation framework Huang, R Stephanie Gamazon, Eric R Genome Med Research Highlight The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent study describes a comprehensive system developed by the Coriell Personalized Medicine Collaborative for facilitating the translation of genomic findings into clinical practice, and its application for seven commonly prescribed drugs. See related Research paper, http://genomemedicine.com/content/5/10/93 BioMed Central 2013-10-18 /pmc/articles/PMC4066637/ /pubmed/24134796 http://dx.doi.org/10.1186/gm497 Text en Copyright © 2013 BioMed Central Ltd.
spellingShingle Research Highlight
Huang, R Stephanie
Gamazon, Eric R
Translating pharmacogenomics discoveries into the clinic: an implementation framework
title Translating pharmacogenomics discoveries into the clinic: an implementation framework
title_full Translating pharmacogenomics discoveries into the clinic: an implementation framework
title_fullStr Translating pharmacogenomics discoveries into the clinic: an implementation framework
title_full_unstemmed Translating pharmacogenomics discoveries into the clinic: an implementation framework
title_short Translating pharmacogenomics discoveries into the clinic: an implementation framework
title_sort translating pharmacogenomics discoveries into the clinic: an implementation framework
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066637/
https://www.ncbi.nlm.nih.gov/pubmed/24134796
http://dx.doi.org/10.1186/gm497
work_keys_str_mv AT huangrstephanie translatingpharmacogenomicsdiscoveriesintotheclinicanimplementationframework
AT gamazonericr translatingpharmacogenomicsdiscoveriesintotheclinicanimplementationframework

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