The Cytotoxicity of Benzaldehyde Nitrogen Mustard-2-Pyridine Carboxylic Acid Hydrazone Being Involved in Topoisomerase IIα Inhibition

The antitumor property of iron chelators and aromatic nitrogen mustard derivatives has been well documented. Combination of the two pharmacophores in one molecule in drug designation is worth to be explored. We reported previously the syntheses and preliminary cytotoxicity evaluation of benzaldehyde...

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Detalles Bibliográficos
Autores principales: Fu, Yun, Zhou, Sufeng, Liu, Youxun, Yang, Yingli, Sun, Xingzhi, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066686/
https://www.ncbi.nlm.nih.gov/pubmed/24995306
http://dx.doi.org/10.1155/2014/527042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066686/
https://www.ncbi.nlm.nih.gov/pubmed/24995306
http://dx.doi.org/10.1155/2014/527042

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