Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases

Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemot...

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Autores principales: França, Paulo H. B., Barbosa, Daniel P., da Silva, Daniel L., Ribeiro, Êurica A. N., Santana, Antônio E. G., Santos, Bárbara V. O., Barbosa-Filho, José M., Quintans, Jullyana S. S., Barreto, Rosana S. S., Quintans-Júnior, Lucindo J., de Araújo-Júnior, João X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066687/
https://www.ncbi.nlm.nih.gov/pubmed/24995289
http://dx.doi.org/10.1155/2014/375423
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author França, Paulo H. B.
Barbosa, Daniel P.
da Silva, Daniel L.
Ribeiro, Êurica A. N.
Santana, Antônio E. G.
Santos, Bárbara V. O.
Barbosa-Filho, José M.
Quintans, Jullyana S. S.
Barreto, Rosana S. S.
Quintans-Júnior, Lucindo J.
de Araújo-Júnior, João X.
author_facet França, Paulo H. B.
Barbosa, Daniel P.
da Silva, Daniel L.
Ribeiro, Êurica A. N.
Santana, Antônio E. G.
Santos, Bárbara V. O.
Barbosa-Filho, José M.
Quintans, Jullyana S. S.
Barreto, Rosana S. S.
Quintans-Júnior, Lucindo J.
de Araújo-Júnior, João X.
author_sort França, Paulo H. B.
collection PubMed
description Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemotherapeutic agents. Furthermore, the emerging resistance against these drugs makes it urgently necessary to discover and develop new, safe and, effective anti-infective agents. In this regard, the aim of this review is to highlight indole alkaloids from marine sources which have been shown to demonstrate activity against infectious diseases.
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spelling pubmed-40666872014-07-03 Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases França, Paulo H. B. Barbosa, Daniel P. da Silva, Daniel L. Ribeiro, Êurica A. N. Santana, Antônio E. G. Santos, Bárbara V. O. Barbosa-Filho, José M. Quintans, Jullyana S. S. Barreto, Rosana S. S. Quintans-Júnior, Lucindo J. de Araújo-Júnior, João X. Biomed Res Int Review Article Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemotherapeutic agents. Furthermore, the emerging resistance against these drugs makes it urgently necessary to discover and develop new, safe and, effective anti-infective agents. In this regard, the aim of this review is to highlight indole alkaloids from marine sources which have been shown to demonstrate activity against infectious diseases. Hindawi Publishing Corporation 2014 2014-06-05 /pmc/articles/PMC4066687/ /pubmed/24995289 http://dx.doi.org/10.1155/2014/375423 Text en Copyright © 2014 Paulo H. B. França et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
França, Paulo H. B.
Barbosa, Daniel P.
da Silva, Daniel L.
Ribeiro, Êurica A. N.
Santana, Antônio E. G.
Santos, Bárbara V. O.
Barbosa-Filho, José M.
Quintans, Jullyana S. S.
Barreto, Rosana S. S.
Quintans-Júnior, Lucindo J.
de Araújo-Júnior, João X.
Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases
title Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases
title_full Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases
title_fullStr Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases
title_full_unstemmed Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases
title_short Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases
title_sort indole alkaloids from marine sources as potential leads against infectious diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066687/
https://www.ncbi.nlm.nih.gov/pubmed/24995289
http://dx.doi.org/10.1155/2014/375423
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