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The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health
Clinical trials, systematic reviews and guidelines compare beneficial and non-beneficial outcomes following interventions. Often, however, various studies on a particular topic do not address the same outcomes, making it difficult to draw clinically useful conclusions when a group of studies is look...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066690/ https://www.ncbi.nlm.nih.gov/pubmed/24957208 http://dx.doi.org/10.1186/1471-2393-14-199 |
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author | Khan, Khalid O’Donovan, Peter |
author_facet | Khan, Khalid O’Donovan, Peter |
author_sort | Khan, Khalid |
collection | PubMed |
description | Clinical trials, systematic reviews and guidelines compare beneficial and non-beneficial outcomes following interventions. Often, however, various studies on a particular topic do not address the same outcomes, making it difficult to draw clinically useful conclusions when a group of studies is looked at as a whole. This problem was recently thrown into sharp focus by a systematic review of interventions for preterm birth prevention, which found that among 103 randomised trials, no fewer than 72 different outcomes were reported. There is a growing recognition among clinical researchers that this variability undermines consistent synthesis of the evidence, and that what is needed is an agreed standardised collection of outcomes - a “core outcomes set” - for all trials in a specific clinical area. Recognising that the current inconsistency is a serious hindrance to progress in our specialty, the editors of over 50 journals related to women’s health have come together to support The CROWN (CoRe Outcomes in WomeN’s health) Initiative. |
format | Online Article Text |
id | pubmed-4066690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40666902014-06-24 The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health Khan, Khalid O’Donovan, Peter BMC Pregnancy Childbirth Editorial Clinical trials, systematic reviews and guidelines compare beneficial and non-beneficial outcomes following interventions. Often, however, various studies on a particular topic do not address the same outcomes, making it difficult to draw clinically useful conclusions when a group of studies is looked at as a whole. This problem was recently thrown into sharp focus by a systematic review of interventions for preterm birth prevention, which found that among 103 randomised trials, no fewer than 72 different outcomes were reported. There is a growing recognition among clinical researchers that this variability undermines consistent synthesis of the evidence, and that what is needed is an agreed standardised collection of outcomes - a “core outcomes set” - for all trials in a specific clinical area. Recognising that the current inconsistency is a serious hindrance to progress in our specialty, the editors of over 50 journals related to women’s health have come together to support The CROWN (CoRe Outcomes in WomeN’s health) Initiative. BioMed Central 2014-06-23 /pmc/articles/PMC4066690/ /pubmed/24957208 http://dx.doi.org/10.1186/1471-2393-14-199 Text en Copyright © 2014 Khan and O'Donovan; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Editorial Khan, Khalid O’Donovan, Peter The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health |
title | The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health |
title_full | The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health |
title_fullStr | The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health |
title_full_unstemmed | The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health |
title_short | The CROWN initiative: journal editors invite researchers to develop core outcomes in women’s health |
title_sort | crown initiative: journal editors invite researchers to develop core outcomes in women’s health |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066690/ https://www.ncbi.nlm.nih.gov/pubmed/24957208 http://dx.doi.org/10.1186/1471-2393-14-199 |
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