The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host–parasite interaction

Babesia spp. are tick-borne, intraerythrocytic hemoparasites that use antigenic variation to resist host immunity, through sequential modification of the parasite-derived variant erythrocyte surface antigen (VESA) expressed on the infected red blood cell surface. We identified the genomic processes...

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Detalles Bibliográficos
Autores principales: Jackson, Andrew P., Otto, Thomas D., Darby, Alistair, Ramaprasad, Abhinay, Xia, Dong, Echaide, Ignacio Eduardo, Farber, Marisa, Gahlot, Sunayna, Gamble, John, Gupta, Dinesh, Gupta, Yask, Jackson, Louise, Malandrin, Laurence, Malas, Tareq B., Moussa, Ehab, Nair, Mridul, Reid, Adam J., Sanders, Mandy, Sharma, Jyotsna, Tracey, Alan, Quail, Mike A., Weir, William, Wastling, Jonathan M., Hall, Neil, Willadsen, Peter, Lingelbach, Klaus, Shiels, Brian, Tait, Andy, Berriman, Matt, Allred, David R., Pain, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066756/
https://www.ncbi.nlm.nih.gov/pubmed/24799432
http://dx.doi.org/10.1093/nar/gku322

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