Cargando…

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

Semen contains relatively ill-defined regulatory components that likely aid fertilization, but which could also interfere with defense against infection. Each ejaculate contains trillions of exosomes, membrane-enclosed subcellular microvesicles, which have immunosuppressive effects on cells importan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vojtech, Lucia, Woo, Sangsoon, Hughes, Sean, Levy, Claire, Ballweber, Lamar, Sauteraud, Renan P., Strobl, Johanna, Westerberg, Katharine, Gottardo, Raphael, Tewari, Muneesh, Hladik, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066774/ https://www.ncbi.nlm.nih.gov/pubmed/24838567 http://dx.doi.org/10.1093/nar/gku347

Ejemplares similares

Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen
por: Gornalusse, Germán, et al.
Publicado: (2023)

The small RNA repertoire of Dictyostelium discoideum and its regulation by components of the RNAi pathway
por: Hinas, Andrea, et al.
Publicado: (2007)

The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function
por: Schaeffer, Daneen, et al.
Publicado: (2012)

Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata
por: Krishna, Srikar, et al.
Publicado: (2013)

2A peptides provide distinct solutions to driving stop-carry on translational recoding
por: Sharma, Pamila, et al.
Publicado: (2012)

RNA-seq analysis of small RNPs in Trypanosoma brucei reveals a rich repertoire of non-coding RNAs
por: Michaeli, Shulamit, et al.
Publicado: (2012)

Auxiliary tRNAs: large-scale analysis of tRNA genes reveals patterns of tRNA repertoire dynamics
por: Wald, Naama, et al.
Publicado: (2014)

Quantitative analysis of processive RNA degradation by the archaeal RNA exosome
por: Hartung, Sophia, et al.
Publicado: (2010)

RNA polyadenylation and degradation in different Archaea; roles of the exosome and RNase R
por: Portnoy, Victoria, et al.
Publicado: (2006)

In vivo cleavage rules and target repertoire of RNase III in Escherichia coli
por: Altuvia, Yael, et al.
Publicado: (2018)

siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2
por: Elkayam, Elad, et al.
Publicado: (2017)

Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome
por: Niemelä, Elina H., et al.
Publicado: (2014)

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans
por: Kalisiak, Katarzyna, et al.
Publicado: (2017)

The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro
por: Drążkowska, Karolina, et al.
Publicado: (2013)

Post-transcriptional repression of CFP-1 expands the regulatory repertoire of LIN-41/TRIM71
por: Kumari, Pooja, et al.
Publicado: (2023)

The SmAP1/2 proteins of the crenarchaeon Sulfolobus solfataricus interact with the exosome and stimulate A-rich tailing of transcripts
por: Märtens, Birgit, et al.
Publicado: (2017)

Genetic interactions suggest multiple distinct roles of the arch and core helicase domains of Mtr4 in Rrp6 and exosome function
por: Klauer, A. Alejandra, et al.
Publicado: (2013)

Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide
por: Kim, Sang-Soo, et al.
Publicado: (2018)

Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation
por: Holub, Peter, et al.
Publicado: (2012)

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
por: Bellingham, Shayne A., et al.
Publicado: (2012)

The C-terminal Region of the Exosome-associated Protein Rrp47 Is Specifically Required for Box C/D Small Nucleolar RNA 3′-Maturation
por: Costello, Joe L., et al.
Publicado: (2011)

A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes
por: Zhong, Fudi, et al.
Publicado: (2015)

Deletion of the nuclear exosome component RRP6 leads to continued accumulation of the histone mRNA HTB1 in S-phase of the cell cycle in Saccharomyces cerevisiae
por: Canavan, Ruth, et al.
Publicado: (2007)

Mucosal effects of tenofovir 1% gel
por: Hladik, Florian, et al.
Publicado: (2015)

Correction: Mucosal effects for tenofovir 1% gel
por: Hladik, Florian, et al.
Publicado: (2015)

The RNA exosome contributes to gene expression regulation during stem cell differentiation
por: Lloret-Llinares, Marta, et al.
Publicado: (2018)

Molecular determinants of HIV-1 NCp7 chaperone activity in maturation of the HIV-1 dimerization initiation site
por: Aduri, Raviprasad, et al.
Publicado: (2013)

SERRATE interacts with the nuclear exosome targeting (NEXT) complex to degrade primary miRNA precursors in Arabidopsis
por: Bajczyk, Mateusz, et al.
Publicado: (2020)

Initial Events in Establishing Vaginal Entry and Infection by Human Immunodeficiency Virus Type-1
por: Hladik, Florian, et al.
Publicado: (2007)

Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNA(Leu(UUR)) with a pathogenic A2748G mutation
por: Tani, Haruna, et al.
Publicado: (2022)

The gateway pDEST17 expression vector encodes a −1 ribosomal frameshifting sequence
por: Belfield, Eric J., et al.
Publicado: (2007)

An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination
por: Haddad, Raphaël, et al.
Publicado: (2012)

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing
por: Chen, Yingxiao, et al.
Publicado: (2023)

Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses
por: Vojtech, Lucia, et al.
Publicado: (2019)

Discovery of microRNAs and other small RNAs in solid tumors
por: Meiri, Eti, et al.
Publicado: (2010)

An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion
por: Collins, Katherine M., et al.
Publicado: (2017)

CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion
por: Tien, Jerry F., et al.
Publicado: (2017)

Spontaneous binding of single-stranded RNAs to RRM proteins visualized by unbiased atomistic simulations with a rescaled RNA force field
por: Krepl, Miroslav, et al.
Publicado: (2022)

RNA processing machineries in Archaea: the 5′-3′ exoribonuclease aRNase J of the β-CASP family is engaged specifically with the helicase ASH-Ski2 and the 3′-5′ exoribonucleolytic RNA exosome machinery
por: Phung, Duy Khanh, et al.
Publicado: (2020)

A functional extracellular transcriptome in animals? implications for biology, disease and medicine
por: Tewari, Muneesh
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_elbjloph8fjqmhfpnpidiv3bff