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TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

TET1 is a 5-methylcytosine dioxygenase and its DNA demethylating activity has been implicated in pluripotency and reprogramming. However, the precise role of TET1 in DNA methylation regulation outside of developmental reprogramming is still unclear. Here, we show that overexpression of the TET1 cata...

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Detalles Bibliográficos
Autores principales:	Jin, Chunlei, Lu, Yue, Jelinek, Jaroslav, Liang, Shoudan, Estecio, Marcos R.H., Barton, Michelle Craig, Issa, Jean-Pierre J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066785/ https://www.ncbi.nlm.nih.gov/pubmed/24875481 http://dx.doi.org/10.1093/nar/gku372

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