Cargando…
A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report
The duodenum is infrequently affected by malignant lymphoma, and follicular lymphomas of the duodenum are rare histological subtypes. There are no reported cases of collision of follicular lymphoma and other tumors in the ampulla of Vater. A 57-year-old Japanese man presented with jaundice, and abdo...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066863/ https://www.ncbi.nlm.nih.gov/pubmed/25002984 http://dx.doi.org/10.1155/2014/530727 |
_version_ | 1782322228484898816 |
---|---|
author | Suzuki, Shioto Tanioka, Fumihiko Inaba, Keisuke Takatori, Shingo Ochiai, Hideto Suzuki, Shohachi |
author_facet | Suzuki, Shioto Tanioka, Fumihiko Inaba, Keisuke Takatori, Shingo Ochiai, Hideto Suzuki, Shohachi |
author_sort | Suzuki, Shioto |
collection | PubMed |
description | The duodenum is infrequently affected by malignant lymphoma, and follicular lymphomas of the duodenum are rare histological subtypes. There are no reported cases of collision of follicular lymphoma and other tumors in the ampulla of Vater. A 57-year-old Japanese man presented with jaundice, and abdominal computed tomography revealed a tumor of the ampulla of Vater invading the pancreatic head with biliary dilatation and a thickened duodenal wall. The patient underwent subtotal stomach-preserving pancreaticoduodenectomy. Histopathology of the resected specimen revealed lymphoid follicular formations with small-to-medium-sized centrocyte-like cells and some centroblast-like cells. The atypical lymphoid cells were immunohistochemically positive for CD10, CD20, and CD79a but negative for CD5 and cyclin D1. BCL2 protein was highly expressed in the follicle centers. The diagnosis was duodenal follicular lymphoma, Grade 1. The follicular lymphoma, 40 mm in diameter, involved duodenal submucosa and regional lymph nodes without distant metastasis. This duodenal follicular lymphoma was partially overlapped by adenocarcinoma of the ampulla of Vater, measuring 25 × 20 mm, which involved the lower common bile duct, pancreas, and duodenum. We report the first case of a surgically treated collision tumor composed of a rare mass-forming follicular lymphoma and adenocarcinoma of the ampulla of Vater. |
format | Online Article Text |
id | pubmed-4066863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-40668632014-07-07 A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report Suzuki, Shioto Tanioka, Fumihiko Inaba, Keisuke Takatori, Shingo Ochiai, Hideto Suzuki, Shohachi Case Rep Pathol Case Report The duodenum is infrequently affected by malignant lymphoma, and follicular lymphomas of the duodenum are rare histological subtypes. There are no reported cases of collision of follicular lymphoma and other tumors in the ampulla of Vater. A 57-year-old Japanese man presented with jaundice, and abdominal computed tomography revealed a tumor of the ampulla of Vater invading the pancreatic head with biliary dilatation and a thickened duodenal wall. The patient underwent subtotal stomach-preserving pancreaticoduodenectomy. Histopathology of the resected specimen revealed lymphoid follicular formations with small-to-medium-sized centrocyte-like cells and some centroblast-like cells. The atypical lymphoid cells were immunohistochemically positive for CD10, CD20, and CD79a but negative for CD5 and cyclin D1. BCL2 protein was highly expressed in the follicle centers. The diagnosis was duodenal follicular lymphoma, Grade 1. The follicular lymphoma, 40 mm in diameter, involved duodenal submucosa and regional lymph nodes without distant metastasis. This duodenal follicular lymphoma was partially overlapped by adenocarcinoma of the ampulla of Vater, measuring 25 × 20 mm, which involved the lower common bile duct, pancreas, and duodenum. We report the first case of a surgically treated collision tumor composed of a rare mass-forming follicular lymphoma and adenocarcinoma of the ampulla of Vater. Hindawi Publishing Corporation 2014 2014-04-28 /pmc/articles/PMC4066863/ /pubmed/25002984 http://dx.doi.org/10.1155/2014/530727 Text en Copyright © 2014 Shioto Suzuki et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Suzuki, Shioto Tanioka, Fumihiko Inaba, Keisuke Takatori, Shingo Ochiai, Hideto Suzuki, Shohachi A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report |
title | A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report |
title_full | A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report |
title_fullStr | A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report |
title_full_unstemmed | A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report |
title_short | A Rare Collision Tumor Composed of Follicular Lymphoma and Adenocarcinoma in the Ampulla of Vater: A Case Report |
title_sort | rare collision tumor composed of follicular lymphoma and adenocarcinoma in the ampulla of vater: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066863/ https://www.ncbi.nlm.nih.gov/pubmed/25002984 http://dx.doi.org/10.1155/2014/530727 |
work_keys_str_mv | AT suzukishioto ararecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT taniokafumihiko ararecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT inabakeisuke ararecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT takatorishingo ararecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT ochiaihideto ararecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT suzukishohachi ararecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT suzukishioto rarecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT taniokafumihiko rarecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT inabakeisuke rarecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT takatorishingo rarecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT ochiaihideto rarecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport AT suzukishohachi rarecollisiontumorcomposedoffollicularlymphomaandadenocarcinomaintheampullaofvateracasereport |