Cargando…

In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles

[Image: see text] The use of RNAs as scaffolds for biomedical applications has several advantages compared with other existing nanomaterials. These include (i) programmability, (ii) precise control over folding and self-assembly, (iii) natural functionalities as exemplified by ribozymes, riboswitche...

Descripción completa

Detalles Bibliográficos
Autores principales:	Afonin, Kirill A., Kasprzak, Wojciech K., Bindewald, Eckart, Kireeva, Maria, Viard, Mathias, Kashlev, Mikhail, Shapiro, Bruce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066900/ https://www.ncbi.nlm.nih.gov/pubmed/24758371 http://dx.doi.org/10.1021/ar400329z

Ejemplares similares

Co-transcriptional production of RNA–DNA hybrids for simultaneous release of multiple split functionalities
por: Afonin, Kirill A., et al.
Publicado: (2014)

Triggerable RNA nanodevices
por: Halman, Justin, et al.
Publicado: (2017)

In vitro Assembly of Cubic RNA-Based Scaffolds Designed in silico
por: Afonin, Kirill A, et al.
Publicado: (2010)

Triggering RNAi with multifunctional RNA nanoparticles and their delivery
por: Dao, Bich Ngoc, et al.
Publicado: (2015)

Triggering of RNA Interference with RNA–RNA, RNA–DNA, and DNA–RNA Nanoparticles
por: Afonin, Kirill A., et al.
Publicado: (2014)

Structural polymorphism of the HIV-1 leader region explored by computational methods
por: Kasprzak, Wojciech, et al.
Publicado: (2005)

Functionally-interdependent shape-switching nanoparticles with controllable properties
por: Halman, Justin R., et al.
Publicado: (2017)

RNA–Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics
por: Bindewald, Eckart, et al.
Publicado: (2018)

RNAJunction: a database of RNA junctions and kissing loops for three-dimensional structural analysis and nanodesign
por: Bindewald, Eckart, et al.
Publicado: (2008)

A Suite of Therapeutically-Inspired Nucleic Acid Logic Systems for Conditional Generation of Single-Stranded and Double-Stranded Oligonucleotides
por: Zakrevsky, Paul, et al.
Publicado: (2019)

Multifunctional RNA Nanoparticles
por: Afonin, Kirill A., et al.
Publicado: (2014)

In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery
por: Kim, Taejin, et al.
Publicado: (2013)

Computational detection of abundant long-range nucleotide covariation in Drosophila genomes
por: Bindewald, Eckart, et al.
Publicado: (2013)

Predicting RNA SHAPE scores with deep learning
por: Bliss, Noah, et al.
Publicado: (2020)

RNA Toehold Interactions Initiate Conditional Gene Silencing
por: Zakrevsky, Paul, et al.
Publicado: (2016)

CorreLogo: an online server for 3D sequence logos of RNA and DNA alignments
por: Bindewald, Eckart, et al.
Publicado: (2006)

Effects of Friedreich's ataxia (GAA)(n)·(TTC)(n) repeats on RNA synthesis and stability
por: Krasilnikova, Maria M., et al.
Publicado: (2007)

CyloFold: secondary structure prediction including pseudoknots
por: Bindewald, Eckart, et al.
Publicado: (2010)

Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain
por: Kim, Taejin, et al.
Publicado: (2020)

RNA–DNA and DNA–DNA base-pairing at the upstream edge of the transcription bubble regulate translocation of RNA polymerase and transcription rate
por: KIreeva, Maria, et al.
Publicado: (2018)

Activation of different split functionalities upon re-association of RNA-DNA hybrids
por: Afonin, Kirill A., et al.
Publicado: (2013)

Break to Build: Isothermal Assembly of Nucleic Acid Nanoparticles (NANPs) via Enzymatic Degradation
por: Beasock, Damian, et al.
Publicado: (2023)

Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism
por: Dangkulwanich, Manchuta, et al.
Publicado: (2013)

Synergistic action of RNA polymerases in overcoming the nucleosomal barrier
por: Jin, Jing, et al.
Publicado: (2010)

Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase
por: Kireeva, Maria L, et al.
Publicado: (2012)

Enzymatic Synthesis of Magnetic Nanoparticles
por: Kolhatkar, Arati G., et al.
Publicado: (2015)

A Genetic Assay for Transcription Errors Reveals Multilayer Control of RNA Polymerase II Fidelity
por: Irvin, Jordan D., et al.
Publicado: (2014)

Synthesis of designer triglycerides by enzymatic acidolysis
por: Kavadia, Monali R., et al.
Publicado: (2018)

RNA nanoparticles for targeted therapies of triple-negative breast cancers
por: Danai, Leyla, et al.
Publicado: (2023)

Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference
por: Santhanam, Arti N., et al.
Publicado: (2009)

Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference
por: Santhanam, Arti N., et al.
Publicado: (2009)

Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles
por: Panigaj, Martin, et al.
Publicado: (2023)

Smart-Responsive Nucleic Acid Nanoparticles (NANPs) with the Potential to Modulate Immune Behavior
por: Chandler, Morgan, et al.
Publicado: (2019)

Genomic Analyses Reveal Broad Impact of miR-137 on Genes Associated with Malignant Transformation and Neuronal Differentiation in Glioblastoma Cells
por: Tamim, Saleh, et al.
Publicado: (2014)

Protein nanoparticles with ligand-binding and enzymatic activities
por: Morozova, Olga V, et al.
Publicado: (2018)

A Cre Transcription Fidelity Reporter Identifies GreA as a Major RNA Proofreading Factor in Escherichia coli
por: Bubunenko, Mikhail G., et al.
Publicado: (2017)

IFNL3 (IL28B) favorable genotype escapes hepatitis C virus-induced microRNAs and mRNA decay
por: McFarland, Adelle P., et al.
Publicado: (2013)

Demonstrating the Synthesis and Antibacterial Properties of Nanostructured Silver
por: Rolband, Lewis, et al.
Publicado: (2023)

The Recognition of and Reactions to Nucleic Acid Nanoparticles by Human Immune Cells
por: Bila, Dominika, et al.
Publicado: (2021)

Virtual Screening of Hepatitis B Virus Pre-Genomic RNA as a Novel Therapeutic Target
por: Olenginski, Lukasz T., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0c55q8ammh53ck58ei2dalo2u0