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Role of metal ions in the cognitive decline of Down syndrome

Down syndrome (DS), caused by trisomy of whole or part of chromosome 21 is the most common mental impairment. All people with DS suffer from cognitive decline and develop Alzheimer’s disease (AD) by the age of 40. The appearance of enlarged early endosomes, followed by Amyloid βpeptide deposition, t...

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Detalles Bibliográficos
Autores principales:	Malakooti, Nakisa, Pritchard, Melanie A., Adlard, Paul A., Finkelstein, David I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066992/ https://www.ncbi.nlm.nih.gov/pubmed/25002847 http://dx.doi.org/10.3389/fnagi.2014.00136

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