The Autolysis of Human HtrA1 Is Governed by the Redox State of Its N-Terminal Domain

[Image: see text] Human HtrA1 (high-temperature requirement protein A1) belongs to a conserved family of serine proteases involved in protein quality control and cell fate. The homotrimeric ubiquitously expressed protease has chymotrypsin-like specificity and primarily targets hydrophobic stretches...

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Detalles Bibliográficos
Autores principales: Risør, Michael W., Poulsen, Ebbe Toftgaard, Thomsen, Line R., Dyrlund, Thomas F., Nielsen, Tania A., Nielsen, Niels Chr., Sanggaard, Kristian W., Enghild, Jan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067144/
https://www.ncbi.nlm.nih.gov/pubmed/24846539
http://dx.doi.org/10.1021/bi401633w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067144/
https://www.ncbi.nlm.nih.gov/pubmed/24846539
http://dx.doi.org/10.1021/bi401633w

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