Phosphomimetic Mutation of Cysteine String Protein-α Increases the Rate of Regulated Exocytosis by Modulating Fusion Pore Dynamics in PC12 Cells

BACKGROUND: Cysteine string protein-α (CSPα) is a chaperone to ensure protein folding. Loss of CSPα function associates with many neurological diseases. However, its function in modulating regulated exocytosis remains elusive. Although cspα-knockouts exhibit impaired synaptic transmission, overexpre...

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Detalles Bibliográficos
Autores principales: Chiang, Ning, Hsiao, Yu-Tien, Yang, Hui-Ju, Lin, Yu-Chun, Lu, Juu-Chin, Wang, Chih-Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067274/
https://www.ncbi.nlm.nih.gov/pubmed/24956274
http://dx.doi.org/10.1371/journal.pone.0099180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067274/
https://www.ncbi.nlm.nih.gov/pubmed/24956274
http://dx.doi.org/10.1371/journal.pone.0099180

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