Individual with Subclinical Atherosclerosis Have Impaired Proliferation of Blood Outgrowth Endothelial Cells, Which Can Be Restored by Statin Therapy

BACKGROUND: To study the regenerative capacity of the endothelium in patients with coronary artery disease (CAD), we cultured blood outgrowth endothelial cells (BOECs) of patients with premature CAD and their first degree relatives (FDR). Additionally we evaluated the influence of statin treatment o...

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Detalles Bibliográficos
Autores principales: Martin-Ramirez, Javier, Kok, Maayke G. M., Hofman, Menno, Bierings, Ruben, Creemers, Esther E., Meijers, Joost C. M., Voorberg, Jan, Pinto-Sietsma, Sara-Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067291/
https://www.ncbi.nlm.nih.gov/pubmed/24955753
http://dx.doi.org/10.1371/journal.pone.0099890

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