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Modulation of Radiation Injury Response in Retinal Endothelial Cells by Quinic Acid Derivative KZ-41 Involves p38 MAPK

Radiation-induced damage to the retina triggers leukostasis, retinal endothelial cell (REC) death, and subsequent hypoxia. Resultant ischemia leads to visual loss and compensatory retinal neovascularization (RNV). Using human RECs, we demonstrated that radiation induced leukocyte adhesion through me...

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Detalles Bibliográficos
Autores principales: Toutounchian, Jordan J., Steinle, Jena J., Makena, Patrudu S., Waters, Christopher M., Wilson, Matthew W., Haik, Barrett G., Miller, Duane D., Yates, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067294/
https://www.ncbi.nlm.nih.gov/pubmed/24956278
http://dx.doi.org/10.1371/journal.pone.0100210

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