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Modulation of Radiation Injury Response in Retinal Endothelial Cells by Quinic Acid Derivative KZ-41 Involves p38 MAPK
Radiation-induced damage to the retina triggers leukostasis, retinal endothelial cell (REC) death, and subsequent hypoxia. Resultant ischemia leads to visual loss and compensatory retinal neovascularization (RNV). Using human RECs, we demonstrated that radiation induced leukocyte adhesion through me...
Autores principales: | Toutounchian, Jordan J., Steinle, Jena J., Makena, Patrudu S., Waters, Christopher M., Wilson, Matthew W., Haik, Barrett G., Miller, Duane D., Yates, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067294/ https://www.ncbi.nlm.nih.gov/pubmed/24956278 http://dx.doi.org/10.1371/journal.pone.0100210 |
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