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Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice

OBJECTIVES: Point-of-care (POC) testing for chlamydia (CT) and gonorrhoea (NG) offers a new approach to the diagnosis and management of these sexually transmitted infections (STIs) in remote Australian communities and other similar settings. Diagnosis of STIs in remote communities is typically sympt...

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Autores principales: Natoli, Lisa, Maher, Lisa, Shephard, Mark, Hengel, Belinda, Tangey, Annie, Badman, Steven G., Ward, James, Guy, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067364/
https://www.ncbi.nlm.nih.gov/pubmed/24956111
http://dx.doi.org/10.1371/journal.pone.0100518
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author Natoli, Lisa
Maher, Lisa
Shephard, Mark
Hengel, Belinda
Tangey, Annie
Badman, Steven G.
Ward, James
Guy, Rebecca J.
author_facet Natoli, Lisa
Maher, Lisa
Shephard, Mark
Hengel, Belinda
Tangey, Annie
Badman, Steven G.
Ward, James
Guy, Rebecca J.
author_sort Natoli, Lisa
collection PubMed
description OBJECTIVES: Point-of-care (POC) testing for chlamydia (CT) and gonorrhoea (NG) offers a new approach to the diagnosis and management of these sexually transmitted infections (STIs) in remote Australian communities and other similar settings. Diagnosis of STIs in remote communities is typically symptom driven, and for those who are asymptomatic, treatment is generally delayed until specimens can be transported to the reference laboratory, results returned and the patient recalled. The objective of this study was to explore the clinical implications of using CT/NG POC tests in routine clinical care in remote settings. METHODS: In-depth qualitative interviews were conducted with a purposively selected group of 18 key informants with a range of sexual health and laboratory expertise. RESULTS: Participants highlighted the potential impact POC testing would have on different stages of the current STI management pathway in remote Aboriginal communities and how the pathway would change. They identified implications for offering a POC test, specimen collection, conducting the POC test, syndromic management of STIs, pelvic inflammatory disease diagnosis and management, interpretation and delivery of POC results, provision of treatment, contact tracing, management of client flow and wait time, and re-testing at 3 months after infection. CONCLUSIONS: The introduction of POC testing to improve STI service delivery requires careful consideration of both its advantages and limitations. The findings of this study will inform protocols for the implementation of CT/NG POC testing, and also STI testing and management guidelines.
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spelling pubmed-40673642014-06-25 Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice Natoli, Lisa Maher, Lisa Shephard, Mark Hengel, Belinda Tangey, Annie Badman, Steven G. Ward, James Guy, Rebecca J. PLoS One Research Article OBJECTIVES: Point-of-care (POC) testing for chlamydia (CT) and gonorrhoea (NG) offers a new approach to the diagnosis and management of these sexually transmitted infections (STIs) in remote Australian communities and other similar settings. Diagnosis of STIs in remote communities is typically symptom driven, and for those who are asymptomatic, treatment is generally delayed until specimens can be transported to the reference laboratory, results returned and the patient recalled. The objective of this study was to explore the clinical implications of using CT/NG POC tests in routine clinical care in remote settings. METHODS: In-depth qualitative interviews were conducted with a purposively selected group of 18 key informants with a range of sexual health and laboratory expertise. RESULTS: Participants highlighted the potential impact POC testing would have on different stages of the current STI management pathway in remote Aboriginal communities and how the pathway would change. They identified implications for offering a POC test, specimen collection, conducting the POC test, syndromic management of STIs, pelvic inflammatory disease diagnosis and management, interpretation and delivery of POC results, provision of treatment, contact tracing, management of client flow and wait time, and re-testing at 3 months after infection. CONCLUSIONS: The introduction of POC testing to improve STI service delivery requires careful consideration of both its advantages and limitations. The findings of this study will inform protocols for the implementation of CT/NG POC testing, and also STI testing and management guidelines. Public Library of Science 2014-06-23 /pmc/articles/PMC4067364/ /pubmed/24956111 http://dx.doi.org/10.1371/journal.pone.0100518 Text en © 2014 Natoli et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Natoli, Lisa
Maher, Lisa
Shephard, Mark
Hengel, Belinda
Tangey, Annie
Badman, Steven G.
Ward, James
Guy, Rebecca J.
Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice
title Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice
title_full Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice
title_fullStr Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice
title_full_unstemmed Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice
title_short Point-of-Care Testing for Chlamydia and Gonorrhoea: Implications for Clinical Practice
title_sort point-of-care testing for chlamydia and gonorrhoea: implications for clinical practice
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067364/
https://www.ncbi.nlm.nih.gov/pubmed/24956111
http://dx.doi.org/10.1371/journal.pone.0100518
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