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Effective Inhibition of c-MET-mediated Signaling, Growth, and Migration of Ovarian Cancer Cells is Influenced by the Ovarian Tissue Microenvironment
The signaling mediated by c-MET and its ligand, hepatocyte growth factor (HGF), has been implicated in malignant progression of cancer involving stimulation of proliferation, invasion, and metastasis. We studied the c-MET/HGF axis as a mediator of tumor-stromal interaction in ovarian cancer and the...
Autores principales: | Kwon, Youngjoo, Smith, Bryan D, Zhou, Yan, Kaufman, Michael D, Godwin, Andrew K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067476/ https://www.ncbi.nlm.nih.gov/pubmed/24362531 http://dx.doi.org/10.1038/onc.2013.539 |
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