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Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene
For expression of genes in mammalian cells, various vectors have been developed using promoters including CMV, EF-1α, and CAG promoters and have been widely used. However, such expression vectors sometimes fail to attain sufficient expression levels depending on the nature of cargo genes and/or on h...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067539/ https://www.ncbi.nlm.nih.gov/pubmed/24526517 http://dx.doi.org/10.1007/s12033-014-9738-0 |