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A Cell-Based High-Throughput Screen Addressing 3′UTR-Dependent Regulation of the MYCN Gene
Neuroblastoma is the most common extracranial solid tumor of infancy. Amplification of MYCN oncogene is found in approximately 20 % of all neuroblastoma patients and correlates with advanced disease stages, rapid tumor progression, and poor prognosis, making this gene an obvious therapeutic target....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067544/ https://www.ncbi.nlm.nih.gov/pubmed/24515800 http://dx.doi.org/10.1007/s12033-014-9739-z |