Cargando…
Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders
Rare copy-number variation (CNV) is an important source of risk for autism spectrum disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic deletions and duplications in affected versus control groups (1.41-fold, p = 1.0 × 10(−5)) and an increase in affected subjec...
Ejemplares similares
-
Genetics of autistic disorders: review and clinical implications
por: Freitag, Christine M., et al.
Publicado: (2009) -
Autism risk factors: genes, environment, and gene-environment interactions
por: Chaste, Pauline, et al.
Publicado: (2012) -
A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder
por: Casey, Jillian P., et al.
Publicado: (2011) -
Individual common variants exert weak effects on the risk for autism spectrum disorders
por: Anney, Richard, et al.
Publicado: (2012) -
High-functioning autism spectrum disorder and fragile X syndrome: report of two affected sisters
por: Chaste, Pauline, et al.
Publicado: (2012)