Microinjection free delivery of miRNA inhibitor into zygotes

The development of gene delivery systems into embryos is challenging due to technical difficulties, delivery efficiency and toxicity. Here, we developed an organic compound (VisuFect)-mediated gene delivery system for zygotes. The VisuFect, which is hydrophilic and Cy5.5-labeled, was conjugated with...

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Detalles Bibliográficos
Autores principales: Joo, Jin Young, Lee, Jonghwan, Ko, Hae Young, Lee, Yong Seung, Lim, Do-Hwan, Kim, Eun-Young, Cho, Sujeong, Hong, Ki-Sung, Ko, Jung Jae, Lee, Suman, Lee, Young Sik, Choi, Youngsok, Lee, Kyung-Ah, Kim, Soonhag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067617/
https://www.ncbi.nlm.nih.gov/pubmed/24957209
http://dx.doi.org/10.1038/srep05417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067617/
https://www.ncbi.nlm.nih.gov/pubmed/24957209
http://dx.doi.org/10.1038/srep05417

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