Cargando…

Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts

BACKGROUND: In vivo studies have demonstrated the ability of multi-walled carbon nanotubes (MWCNT) to induce airway remodeling, a key feature of chronic respiratory diseases like asthma and chronic obstructive pulmonary disease. However, the mechanism leading to remodeling is poorly understood. Part...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hussain, Salik, Sangtian, Stacey, Anderson, Shamika M, Snyder, Ryan J, Marshburn, Jamie D, Rice, Annette B, Bonner, James C, Garantziotis, Stavros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067690/ https://www.ncbi.nlm.nih.gov/pubmed/24915862 http://dx.doi.org/10.1186/1743-8977-11-28

Ejemplares similares

Multiwalled carbon nanotubes induce altered morphology and loss of barrier function in human bronchial epithelium at noncytotoxic doses
por: Snyder, Ryan J, et al.
Publicado: (2014)

Impaired Ciliogenesis in differentiating human bronchial epithelia exposed to non-Cytotoxic doses of multi-walled carbon Nanotubes
por: Snyder, Ryan J., et al.
Publicado: (2017)

Cerium dioxide nanoparticles do not modulate the lipopolysaccharide-induced inflammatory response in human monocytes
por: Hussain, Salik, et al.
Publicado: (2012)

Effects of inhaled high-molecular weight hyaluronan in inflammatory airway disease
por: Lamas, Adelaida, et al.
Publicado: (2016)

Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo
por: Taylor, Alexia J., et al.
Publicado: (2014)

Mechanical regulation of cardiac fibroblast profibrotic phenotypes
por: Herum, Kate M., et al.
Publicado: (2017)

Long-term polarization of alveolar macrophages to a profibrotic phenotype after inhalation exposure to multi-wall carbon nanotubes
por: Otsuka, Kunihiro, et al.
Publicado: (2018)

TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts
por: Noguchi, Satoshi, et al.
Publicado: (2017)

Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
por: Blokland, Kaj E. C., et al.
Publicado: (2021)

Substrate Stiffness and Stretch Regulate Profibrotic Mechanosignaling in Pulmonary Arterial Adventitial Fibroblasts
por: Wang, Ariel, et al.
Publicado: (2021)

Profibrotic behavior of fibroblasts derived from patients that develop posttraumatic shoulder stiffness
por: Hendy, Benjamin A., et al.
Publicado: (2023)

Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts
por: Tannheimer, Stacey L, et al.
Publicado: (2012)

Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses
por: Manuyakorn, Wiparat, et al.
Publicado: (2016)

GPCR-induced YAP activation sensitizes fibroblasts to profibrotic activity of TGFβ1
por: Zmajkovicova, Katarina, et al.
Publicado: (2020)

The uPA System Differentially Alters Fibroblast Fate and Profibrotic Ability in Skin Fibrosis
por: Zou, Ming-Li, et al.
Publicado: (2022)

Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis
por: Jia, Minxue, et al.
Publicado: (2023)

Vitamin C Regulates the Profibrotic Activity of Fibroblasts in In Vitro Replica Settings of Myocardial Infarction
por: Xu, Yichen, et al.
Publicado: (2023)

The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method
por: Taylor-Just, Alexia J., et al.
Publicado: (2020)

Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis
por: Motz, Kevin M., et al.
Publicado: (2023)

New Insights into Profibrotic Myofibroblast Formation in Systemic Sclerosis: When the Vascular Wall Becomes the Enemy
por: Romano, Eloisa, et al.
Publicado: (2021)

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis
por: Chakraborty, Debomita, et al.
Publicado: (2017)

Transforming Growth Factor Beta 1 Stimulates Profibrotic Activities of Luteal Fibroblasts in Cows(1)
por: Maroni, Dulce, et al.
Publicado: (2012)

IL-11 Is Elevated and Drives the Profibrotic Phenotype Transition of Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy
por: Wu, Pengsen, et al.
Publicado: (2022)

Immune complexes containing scleroderma-specific autoantibodies induce a profibrotic and proinflammatory phenotype in skin fibroblasts
por: Raschi, Elena, et al.
Publicado: (2018)

Effects of selexipag and its active metabolite in contrasting the profibrotic myofibroblast activity in cultured scleroderma skin fibroblasts
por: Cutolo, Maurizio, et al.
Publicado: (2018)

Thin single-wall BN-nanotubes formed inside carbon nanotubes
por: Nakanishi, Ryo, et al.
Publicado: (2013)

Macrophages promote a profibrotic phenotype in orbital fibroblasts through increased hyaluronic acid production and cell contractility
por: Yang, I-Hui, et al.
Publicado: (2019)

Author Correction: Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis
por: Chakraborty, Debomita, et al.
Publicado: (2021)

Rutin-Functionalized Multi-Walled Carbon Nanotubes: Molecular Docking, Physicochemistry and Cytotoxicity in Fibroblasts
por: Neto, Conrado M. S., et al.
Publicado: (2021)

B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis
por: François, Antoine, et al.
Publicado: (2013)

Inhibitory Effects of Short-Chain Fatty Acids and ω-3 Polyunsaturated Fatty Acids on Profibrotic Factors in Dermal Fibroblasts
por: Maeshige, Noriaki, et al.
Publicado: (2019)

SB203580—A Potent p38 MAPK Inhibitor Reduces the Profibrotic Bronchial Fibroblasts Transition Associated with Asthma
por: Paw, Milena, et al.
Publicado: (2021)

Multi-walled carbon nanotubes induce human microvascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells
por: Snyder-Talkington, Brandi N, et al.
Publicado: (2013)

The Role of the Extracellular Matrix Protein Mindin in Airway Response to Environmental Airways Injury
por: Frush, Sarah, et al.
Publicado: (2011)

Retraction: “The Role of the Extracellular Matrix Protein Mindin in Airway Response to Environmental Airways Injury”
por: Frush, Sarah, et al.
Publicado: (2016)

Profibrotic pathways and atrial cardiomyopathy in persistent atrial fibrillation
por: Canpolat, Uğur
Publicado: (2016)

Profibrotic mediators in tendon disease: a systematic review
por: Morita, Wataru, et al.
Publicado: (2016)

Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived from Peyronie's plaque
por: Choi, Min Ji, et al.
Publicado: (2015)

CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis
por: XU, HONGHAI, et al.
Publicado: (2015)

Upregulation of allograft inflammatory factor-1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype
por: Li, Yushu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jbn4stpvnmhsfd2919euml1el9