Cargando…
Spinal 5-HT(3) receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascade
BACKGROUND: It has been recently recognized that the descending serotonin (5-HT) system from the rostral ventromedial medulla (RVM) in the brainstem and the 5-HT(3) receptor subtype in the spinal dorsal horn are involved in enhanced descending pain facilitation after tissue and nerve injury. However...
Autores principales: | Guo, Wei, Miyoshi, Kan, Dubner, Ronald, Gu, Ming, Li, Man, Liu, Jian, Yang, Jiale, Zou, Shiping, Ren, Ke, Noguchi, Koichi, Wei, Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067691/ https://www.ncbi.nlm.nih.gov/pubmed/24913307 http://dx.doi.org/10.1186/1744-8069-10-35 |
Ejemplares similares
-
Altered glial glutamate transporter expression in descending circuitry and the emergence of pain chronicity
por: Guo, Wei, et al.
Publicado: (2019) -
Long lasting pain hypersensitivity following ligation of the tendon of the masseter muscle in rats: A model of myogenic orofacial pain
por: Guo, Wei, et al.
Publicado: (2010) -
Differential involvement of trigeminal transition zone and laminated subnucleus caudalis in orofacial deep and cutaneous hyperalgesia: the effects of interleukin-10 and glial inhibitors
por: Shimizu, Kohei, et al.
Publicado: (2009) -
Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat
por: Asante, Curtis O., et al.
Publicado: (2010) -
Spinal facilitation of descending motor input
por: Taccola, Giuliano, et al.
Publicado: (2023)