Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres

The budding yeast centromere contains Cse4, a specialized histone H3 variant. Fluorescence pulse-chase analysis of an internally tagged Cse4 reveals that it is replaced with newly synthesized molecules in S phase, remaining stably associated with centromeres thereafter. In contrast, C-terminally-tag...

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Detalles Bibliográficos
Autores principales: Wisniewski, Jan, Hajj, Bassam, Chen, Jiji, Mizuguchi, Gaku, Xiao, Hua, Wei, Debbie, Dahan, Maxime, Wu, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067749/
https://www.ncbi.nlm.nih.gov/pubmed/24844245
http://dx.doi.org/10.7554/eLife.02203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067749/
https://www.ncbi.nlm.nih.gov/pubmed/24844245
http://dx.doi.org/10.7554/eLife.02203

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